CNN1 and NCAPD2

Number of citations of the paper that reports this interaction (PubMedID 27107012)
72

Data Source:
BioGRID (two hybrid)

		CNN1	NCAPD2
Description		calponin 1	non-SMC condensin I complex subunit D2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoskeleton Focal Adhesion Actin Cytoskeleton	Nuclear Chromosome Condensed Chromosome, Centromeric Region Condensed Chromosome Condensed Nuclear Chromosome Condensin Complex Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Membrane Centriolar Satellite Ciliary Basal Body
	Molecular Function	Actin Binding Protein Binding Calmodulin Binding Actin Filament Binding	Protein Binding Histone Binding
	Biological Process	Regulation Of Smooth Muscle Contraction Actin Filament Organization Actomyosin Structure Organization Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation	Mitotic Cell Cycle Mitotic Chromosome Condensation Meiotic Chromosome Condensation Chromosome Condensation Cell Division Positive Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Separation Positive Regulation Of Chromosome Condensation
Pathways		Developmental Lineage of Mammary Gland Myoepithelial Cells	Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Presence of antiphospholipid antibodies ( 27098658)
Interacting Genes		15 interacting genes: ACTA1 ADRB2 CALM1 CCHCR1 COG6 DNMBP FYN MYO1A NCAPD2 PLRG1 PRKCE SYCE1 TFPT TPM3 TUBB	7 interacting genes: CDC42 CDK1 CNN1 CSNK2A1 SMC2 SMC4 SUMO2
Entrez ID		1264	9918
HPRD ID		02884	06472
Ensembl ID		ENSG00000130176	ENSG00000010292
Uniprot IDs		B7Z7E1 P51911 Q53FP8 V9HWA5	B3KMS0 B3KY03 Q15021
PDB IDs		1WYP
Enriched GO Terms of Interacting Partners?		Actin Filament Chromosome Organization Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Cell Body Mitotic Chromosome Condensation Cellular Response To Prostaglandin E Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Prostaglandin Stimulus Regulation Of Metal Ion Transport Response To Prostaglandin E Mitotic Cell Cycle Protein-containing Complex Binding Regulation Of Calcium Ion Transmembrane Transport Cell Cycle Phase Transition Fc-gamma Receptor Signaling Pathway Condensed Chromosome Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Regulation Of Monoatomic Ion Transport Innate Immune Response-activating Signaling Pathway Cellular Response To Glycine Response To Singlet Oxygen Toll-like Receptor 4 Signaling Pathway Cell Surface Toll-like Receptor Signaling Pathway Chromosome Condensation Cell Division Muscle Contraction Glutamate Receptor Signaling Pathway Cellular Response To Amyloid-beta Activation Of Innate Immune Response Cytoplasm Sarcomere Cellular Response To Oxygen-containing Compound Positive Regulation Of Organelle Organization Modulation Of Chemical Synaptic Transmission Cell Cycle G2/M Phase Transition Regulation Of Calcium Ion Transport Fc Receptor Signaling Pathway Cell Surface Pattern Recognition Receptor Signaling Pathway Chromosome Organization Involved In Meiotic Cell Cycle Response To Amyloid-beta Beta2-adrenergic Receptor Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Glycine Ethanol Binding Regulation Of Chromosome Organization Muscle System Process	Regulation Of Chromosome Segregation Positive Regulation Of Chromosome Segregation Chromosome Condensation Positive Regulation Of Cell Cycle Process Regulation Of Chromosome Separation Condensin Complex Meiotic Chromosome Condensation Positive Regulation Of Chromosome Condensation Regulation Of Cell Cycle Process Positive Regulation Of Cell Cycle Positive Regulation Of Chromosome Organization Meiotic Chromosome Segregation Regulation Of Chromosome Condensation Mitotic Chromosome Condensation Kinetochore Organization Regulation Of Cell Cycle Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Organelle Organization Protein Localization To Site Of Double-strand Break Positive Regulation Of Chromosome Separation Regulation Of Chromosome Organization Positive Regulation Of Growth Organelle Organization Condensed Nuclear Chromosome Nuclear Chromosome Segregation Chromosome Organization Involved In Meiotic Cell Cycle Pronuclear Fusion Chromosome Organization Nucleotide Binding Mitotic DNA-templated DNA Replication Cyclin B1-CDK1 Complex Cyclin A1-CDK1 Complex Cyclin A2-CDK1 Complex Cell Division DNA Damage Checkpoint Signaling GBD Domain Binding Storage Vacuole Nuclear Division Positive Regulation Of Cellular Component Organization Protein Localization To Chromosome Mitotic DNA Replication DNA Synthesis Involved In Mitotic DNA Replication Golgi Organization Regulation Of Organelle Organization Chromatin Binding Cyclin-dependent Protein Kinase Activity Supramolecular Fiber Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body
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