MS4A3 and SMCO4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MS4A3	SMCO4
Description		membrane spanning 4-domains A3	single-pass membrane protein with coiled-coil domains 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Endomembrane System Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Alzheimer's disease ( 24755620) Vitamin B12 levels ( 22367966)	Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		38 interacting genes: ADIPOQ ARLN ATP6V0B BMP10 BNIP3 CCDC167 CD53 CD72 CDKN3 CLDN1 CLDN6 EFNA5 EMP3 ERG28 IFITM3 IGFBP5 MS4A13 NKG7 PLP1 PLPP6 SEC22A SGTA SLC22A14 SLC5A4 SMCO4 SMIM3 STX8 TEX264 TM4SF18 TMBIM6 TMEM107 TMEM140 TMEM182 TMEM218 TMEM239 VKORC1L1 YIPF6 ZFPL1	62 interacting genes: AQP6 ARL13B BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35H1 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1
Entrez ID		932	56935
HPRD ID		09403	17008
Ensembl ID		ENSG00000149516	ENSG00000166002
Uniprot IDs		Q96HJ5	Q9NRQ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Protein Binding
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