SMCO4 and SYNPR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMCO4	SYNPR
Description		single-pass membrane protein with coiled-coil domains 4	synaptoporin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Synapse
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Insulin levels in response to oral glucose tolerance test (30 minutes) ( 29093273) Liver enzyme levels (alanine transaminase) ( 33972514)	Autism ( 30675382) Congenital heart disease (inherited effect) ( 28468790) Congenital left-sided heart lesions ( 25138779) Idiopathic downbeat nystagmus ( 32157568) Lean body mass ( 28552196) Major depressive disorder ( 29317602)
Interacting Genes		62 interacting genes: AQP6 ARL13B BNIP3L CD79A CLEC10A CLTRN CPLX4 CREB3L1 CXCR2 EBP ELOVL4 ERGIC3 FAM174A FAM209A FAM210B FFAR2 GJA8 GKN1 GPA33 GPR152 GPR42 HHLA2 ICAM3 IL10RA KASH5 KCNK5 KIR3DL1 KRT40 KRTAP10-3 KRTAP10-7 LEPROTL1 LMNA LRRC25 M6PR MGST3 MS4A3 MUC1 PEX12 PLD3 PTGES RETREG3 SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35H1 SLC41A3 SLC7A1 SLC7A14 SMIM3 SPINT1 STOM SUSD3 SYNE4 SYNPR TEX29 TFEC TMEM139 TMEM80 TMX2 VSIR WBP1	11 interacting genes: ARLN CREB3 DOLK FATE1 GALNT15 GPR37L1 KTN1 PLPP6 SLC1A1 SMCO4 TRARG1
Entrez ID		56935	132204
HPRD ID		17008	15458
Ensembl ID		ENSG00000166002	ENSG00000163630
Uniprot IDs		Q9NRQ5	Q8TBG9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding	Endoplasmic Reticulum Membrane Membrane Endoplasmic Reticulum D-aspartate Transmembrane Transporter Activity Positive Regulation Of Deacetylase Activity Dolichol Kinase Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Response To Anesthetic Conditioned Place Preference D-aspartate Import Across Plasma Membrane Cysteine Transmembrane Transport Intracellular Glutamate Homeostasis Vesicle-mediated Transport To The Plasma Membrane Cysteine Transport High-affinity L-glutamate Transmembrane Transporter Activity D-aspartate Transmembrane Transport Cysteine Transmembrane Transporter Activity Response To Ammonium Ion Cellular Response To Ammonium Ion Cellular Response To Mercury Ion Distal Dendrite Glutamate:sodium Symporter Activity Response To Bisphenol A Perisynaptic Space L-aspartate Import Across Plasma Membrane Cellular Response To Bisphenol A Prosaposin Receptor Activity Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation CCR1 Chemokine Receptor Binding Release From Viral Latency Terpenoid Metabolic Process Isoprenoid Metabolic Process Dolichol Phosphate Mannose Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration Glucose Import In Response To Insulin Stimulus Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Geranyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Positive Regulation Of Neutrophil Activation
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