COPS2 and PSMD4

  • Number of citations of the paper that reports this interaction (PMID 10903862)
  • 28
  • Data Source:
  • BioGRID (enzymatic study)

COPS2

PSMD4

Gene Name COP9 signalosome subunit 2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 CSNK2A1 CSNK2B CUL1 CUL4A CUL5 DDB1 EP300 GFER GPS1 HIST1H3A HIST1H4A ING1 ING2 IP6K1 IRF8 JUN MAP3K10 MAPK8 NCOR1 NIF3L1 NR0B1 NR2F1 PRKD1 PSMD4 RARA RXRA SENP8 SIN3A SIN3B THRA THRB TP53 VDR 41 interactors: ADRM1 APP BTRC CCNA2 CCNB1 COPS2 COPS7A CUL1 EGFR ELSPBP1 FBXO25 FLOT1 GNB5 ID1 MDM2 MYOD1 NEDD4 NEDD4L NEDD8 NUB1 NUPR1 PARK2 PSMC2 RAD23A RAD23B RASSF8 RBCK1 SCHIP1 SIAH2 SREBF2 STUB1 TCF3 TRIM63 UBB UBC UBE2C UBE3A UBQLN1 UBQLN2 UBQLN4 XPC
Entrez ID 9318 5710
HPRD ID 05146 03386
Ensembl ID ENSG00000166200 ENSG00000159352
Uniprot IDs P61201 Q59EL2 P55036 Q5VWC4
PDB IDs 1P9C 1P9D 1UEL 1YX4 1YX5 1YX6 2KDE 2KDF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
confirm  degradation  demonstrating  dominant  e3  exploited  extend  incorporated  interacting  interferring  ligase  mdm2  modulate  motifs  p53  participates  proteasomal  proteasome  recognition  rescue  rpn10  s5a  selectively  selectivity  stabilization  ubiquitin  ubiquitinated  uim  uims 
Tagcloud (Difference) ?
confirm  degradation  demonstrating  dominant  e3  exploited  extend  incorporated  interacting  interferring  ligase  mdm2  modulate  motifs  p53  participates  proteasomal  proteasome  recognition  rescue  rpn10  s5a  selectively  selectivity  stabilization  ubiquitin  ubiquitinated  uim  uims 
Tagcloud (Intersection) ?