ARRDC1 and PDCD6IP

Number of citations of the paper that reports this interaction (PMID 21191027)
22

Data Source:
BioGRID (two hybrid, two hybrid)

		ARRDC1	PDCD6IP
Gene Name		arrestin domain containing 1	programmed cell death 6 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cytoplasmic Vesicle Extracellular Vesicular Exosome	Immunological Synapse Cytoplasm Microtubule Organizing Center Cytosol Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Endoplasmic Reticulum Exit Site
	Molecular Function		Protein Binding SH3 Domain Binding Proteinase Activated Receptor Binding Protein Homodimerization Activity Calcium-dependent Protein Binding
	Biological Process		Cell Separation After Cytokinesis Apoptotic Process Nucleus Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Viral Life Cycle Viral Budding Via Host ESCRT Complex Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Extracellular Vesicular Exosome Assembly
Pathways			HIV Life Cycle Budding and maturation of HIV virion Uptake and actions of bacterial toxins HIV Infection Uptake and function of anthrax toxins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738)
Protein-Protein Interactions		7 interactors: APP ITCH NEDD4 PDCD6IP TSG101 WWP1 WWP2	35 interactors: ARRDC1 ARRDC3 ATN1 CD2AP CEP55 CHMP4A CHMP4B CHMP4C CXCR1 EGFR F2R GRB2 HOXA1 ITSN1 ITSN2 KEAP1 MAPK6 PDCD6 PTK2B RAMP3 RNF11 SDCBP SH3GL1 SH3GL2 SH3GL3 SH3KBP1 SH3RF1 SRC TAB1 TNIP2 TSG101 TTF2 VPS28 VPS37C YES1
Entrez ID		92714	10015
HPRD ID		12491	06425
Ensembl ID		ENSG00000197070	ENSG00000170248
Uniprot IDs		Q8N5I2	C5MQH7 Q8WUM4
PDB IDs			2OEV 2OEW 2OEX 2OJQ 2R02 2R03 2R05 2XS1 2XS8 2ZNE 3C3O 3C3Q 3C3R 3E1R 4JJY
Enriched GO Terms of Interacting Partners?		Viral Life Cycle Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Interaction With Host Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Viral Entry Into Host Cell Entry Into Host Cell Proteolysis Regulation Of Extracellular Vesicular Exosome Assembly Catabolic Process Viral Budding Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cellular Protein Metabolic Process Locomotion Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Virion Assembly Intracellular Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Protein Metabolic Process Cellular Protein Modification Process Regulation Of Potassium Ion Transmembrane Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuromuscular Junction Development Positive Regulation Of Exocytosis Regulation Of Potassium Ion Transport Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Membrane Budding Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Negative Regulation Of Biosynthetic Process Regulation Of Synapse Structure Or Activity	Virion Assembly Locomotion Endocytosis Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Cell Migration Cell Separation After Cytokinesis Membrane Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Axon Guidance Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Chemotaxis Viral Budding Transport Regulation Of Signal Transduction Viral Life Cycle Regulation Of Cellular Process Establishment Of Protein Localization Endosomal Transport Viral Protein Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Axonogenesis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of ERBB Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Signal Transduction Viral Process Axon Development Regulation Of Signaling Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Regulation Of MAPK Cascade Neuron Projection Morphogenesis Regulation Of Intracellular Signal Transduction Cell Projection Organization Response To Organic Substance Multicellular Organismal Development Regulation Of Organelle Organization Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Vacuolar Transport Positive Regulation Of Metabolic Process Intracellular Transport Neuron Development Anatomical Structure Development Apoptotic Process Cell Morphogenesis Involved In Differentiation
Tagcloud ?			129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Difference) ?			129n 146n adjuvanted arepanrix batch batches deamidation dige dioxidation fabp focetria gallus glycosylation h1n1 ha1 ha2 hemagglutinin latticed ma1 manufacturing narcolepsy neuraminidase nucleoprotein pandemrix ph1n1 sulfation tspan8 tub vaccines
Tagcloud (Intersection) ?