ARRDC1 and MTURN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARRDC1	MTURN
Description		arrestin domain containing 1	maturin, neural progenitor differentiation regulator homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane Cytoplasmic Vesicle Extracellular Exosome Extracellular Vesicle	Cytoplasm
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity Arrestin Family Protein Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Extracellular Transport Protein Transport Protein Ubiquitination Negative Regulation Of Notch Signaling Pathway Extracellular Vesicle Biogenesis	Regulation Of Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433)	Cadmium levels ( 26025379)
Interacting Genes		8 interacting genes: APP DAPK1 EPN2 FAM13A-AS1 MTDH MTURN PDCD6IP UBASH3A	23 interacting genes: AP2M1 APP ARRDC1 DAZAP2 MKRN1 PLEKHB2 REL RNF41 RPS27A SH3RF1 SSX1 SUSD6 TMEM239 TNFRSF19 TP53BP2 TRAF6 TRIM38 TRIM39 TRIM5 TRIM8 UBA52 UBB UBC
Entrez ID		92714	222166
HPRD ID		12491	07635
Ensembl ID		ENSG00000197070	ENSG00000180354
Uniprot IDs		Q8N5I2	Q8N3F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Regulation Of Signal Transduction Amylin Binding Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Cell Communication Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Signaling Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Extracellular Vesicle Biogenesis Extracellular Exosome Biogenesis Positive Regulation Of Extracellular Exosome Assembly Bicellular Tight Junction Proteinase Activated Receptor Binding Actomyosin Contractile Ring Assembly Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Positive Regulation Of Autophagy Regulation Of Extracellular Exosome Assembly Intercellular Canaliculus	Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Protein Tag Activity Ubiquitin Protein Ligase Activity Protein Modification Process Endocytic Vesicle Membrane Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Canonical NF-kappaB Signal Transduction Protein Polyubiquitination Ubiquitin Protein Ligase Binding Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of JNK Cascade Innate Immune Response Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Proteolysis Involved In Protein Catabolic Process Endosome Membrane Defense Response To Symbiont Regulation Of JNK Cascade Positive Regulation Of Cell Communication Defense Response To Other Organism Positive Regulation Of Signaling Canonical NF-kappaB Signal Transduction Modification-dependent Protein Catabolic Process Vesicle Protein Autoubiquitination Regulation Of Protein Catabolic Process Protein K63-linked Ubiquitination Mitochondrial Outer Membrane Regulation Of Signal Transduction Regulation Of MAPK Cascade Cytosol Suppression Of Viral Release By Host Identical Protein Binding Positive Regulation Of MAPK Cascade Macromolecule Catabolic Process Regulation Of Viral Entry Into Host Cell Protein Serine/threonine Kinase Binding Host-mediated Suppression Of Symbiont Invasion Response To Other Organism Zinc Ion Binding Transcription Coactivator Activity Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Receptor Internalization Regulation Of Cell Communication Regulation Of Signaling Regulation Of Lipopolysaccharide-mediated Signaling Pathway Proteolysis
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