CUX1 and SATB1

Number of citations of the paper that reports this interaction (PMID 10373541)
18

Data Source:
HPRD (in vivo, in vitro)

		CUX1	SATB1
Gene Name		cut-like homeobox 1	SATB homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Integral Component Of Golgi Membrane	Nucleus Nucleoplasm Nuclear Heterochromatin Nuclear Matrix PML Body
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Chromatin Binding Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Intra-Golgi Vesicle-mediated Transport Multicellular Organismal Development Lung Development Auditory Receptor Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Dendrite Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Remodeling Transcription, DNA-templated Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Epidermis Development Viral Process Histone Methylation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Activated T Cell Proliferation Reflex
Pathways		Signaling by FGFR in disease Signaling by FGFR1 mutants Signaling by FGFR mutants Signaling by FGFR1 fusion mutants	Apoptotic cleavage of cellular proteins Programmed Cell Death Apoptotic execution phase
Drugs
Diseases
GWAS		Response to antidepressants ( 22584459)	Platelet counts ( 22139419)
Protein-Protein Interactions		20 interactors: BIN1 CA12 CCNA1 CDC25A CDK1 CDK7 CREBBP CTSL CYTH2 EHMT2 ELAC2 GOLGA5 HMGB1 KAT2B MAX RB1 RECQL5 SATB1 SDC3 TLE4	23 interactors: BAZ1A CASP6 CBX4 CHD3 CUX1 DYT10 EP300 GATA3 HDAC1 KAT2B MTA2 PIAS1 PIAS3 PIAS4 POLR2J SIRT1 SMARCA5 SUMO1 SUMO1P1 SUMO3 TOPORS UBE2I UBR5
Entrez ID		1523	6304
HPRD ID		00295	03647
Ensembl ID		ENSG00000257923	ENSG00000182568
Uniprot IDs		P39880 Q13948 Q3LIA3	Q01826
PDB IDs			1YSE 2L1P 2O49 2O4A 3NZL 3TUO
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization G1/S Transition Of Mitotic Cell Cycle Chromatin Modification Negative Regulation Of Gene Expression Chromosome Organization Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cell Division Cell Cycle Process Chromatin Organization Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter N-terminal Peptidyl-lysine Acetylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle Viral Process Mitotic Nuclear Division Regulation Of Cell Cycle Cell Cycle Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Histone Modification Mitotic Cell Cycle Process Chromatin Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Protein Kinase Activity Negative Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Kinase Activity Regulation Of Nucleic Acid-templated Transcription Protein Localization To Chromosome, Centromeric Region Regulation Of RNA Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Catalytic Activity Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Apoptotic Process Regulation Of Gene Expression Programmed Cell Death Regulation Of Nitrogen Compound Metabolic Process Cell Death	Protein Sumoylation Peptidyl-lysine Modification Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Modification By Small Protein Conjugation RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peptidyl-amino Acid Modification Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Chromatin Modification Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Positive Regulation Of Metabolic Process Gene Expression Chromatin Remodeling Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cellular Protein Modification Process Chromosome Organization Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Sumoylation Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of Protein Sumoylation Positive Regulation Of Transcription, DNA-templated Regulation Of Androgen Receptor Signaling Pathway Cellular Protein Metabolic Process
Tagcloud ?		accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Difference) ?		accumulated activators ancillary base burden cut ectopic excision framework haploinsufficiency homeobox implicated isoform isoforms mechanistic opposite paradoxically progression promotes protection reconcile repressors supports suppression transgenic tumorigenesis tumour whereby yet	biomarker clinicopathologic confidence depth endometrial federation gynecology hazards histological international interval invasion lymphatic metastasis myometrial node obstetrics organizer overexpressed parameter predicting prognostic rich serve serves special treating untreated worse
Tagcloud (Intersection) ?