CD7 and LGALS1

Number of citations of the paper that reports this interaction (PubMedID 10490978)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		CD7	LGALS1
Description		CD7 molecule	galectin 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Extracellular Matrix Extracellular Exosome Galectin Complex
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Signaling Receptor Activity	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Laminin Binding Receptor Ligand Activity
	Biological Process	Adaptive Immune Response Immune System Process Positive Regulation Of T Cell Cytokine Production Immune Response Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Interleukin-2-mediated Signaling Pathway T Cell Activation	Plasma Cell Differentiation Apoptotic Process Signal Transduction T Cell Costimulation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of Inflammatory Response Cell-cell Adhesion Negative Regulation Of T-helper 17 Cell Lineage Commitment Positive Regulation Of Dendritic Cell Differentiation
Pathways			Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol OTX-008
Diseases
GWAS		Blood protein levels ( 30072576)	Fat distribution (HIV) ( 21897333)
Interacting Genes		9 interacting genes: CPTP CTSL LGALS1 NFKBIA PI4KA PIK3R1 SEC22A SECTM1 SNAP29	17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1
Entrez ID		924	3956
HPRD ID		01732	01040
Ensembl ID		ENSG00000173762	ENSG00000100097
Uniprot IDs		P09564 Q29VG3	A0A384MR27 P09382
PDB IDs			1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83 6M5Y 7LTA 7NML 8B0W 8B0Z 8OJP 8R74 8RDC
Enriched GO Terms of Interacting Partners?		Membrane Organization Serpin Family Protein Binding Fusion Of Virus Membrane With Host Endosome Membrane Plasma Membrane Membrane Fusion Lactose Binding Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cytokine Production Regulation Of Protein Import Into Nucleus Phosphatidylinositol Phosphate Biosynthetic Process Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication SNAP Receptor Activity Macrophage Apoptotic Process Elastin Catabolic Process Fusion Of Virus Membrane With Host Plasma Membrane Immune System Process Chromaffin Granule Enkephalin Processing B Cell Differentiation Regulation Of Immune Response Positive Regulation Of Immune System Process Galectin Complex Receptor Ligand Activity Negative Regulation Of Hemopoiesis Lymphocyte Activation Involved In Immune Response Regulation Of Hemopoiesis Negative Regulation Of Multicellular Organismal Process Cytokine-mediated Signaling Pathway Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Transport Protein Import Into Nucleus I-kappaB/NF-kappaB Complex Negative Regulation Of Myeloid Cell Differentiation Kinase Regulator Activity Perinuclear Endoplasmic Reticulum Membrane Phosphatidylinositol Biosynthetic Process Phosphatidylinositol Metabolic Process 1-phosphatidylinositol 4-kinase Activity Ciliary Pocket Membrane Elastin Metabolic Process Endolysosome Lumen Inflammatory Cell Apoptotic Process Leukocyte Activation Involved In Immune Response Positive Regulation Of Dendritic Cell Differentiation Cell Activation Involved In Immune Response Plasma Cell Differentiation Regulation Of Intracellular Protein Transport Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Establishment Of Protein Localization	External Side Of Plasma Membrane Lymphocyte Activation T Cell Activation Leukocyte Activation Cell Adhesion Cell Activation Immune System Process T Cell Selection Rhythmic Synaptic Transmission Signaling Receptor Activity Heterotypic Cell-cell Adhesion Positive Regulation Of Cytokine Production Mononuclear Cell Differentiation Positive Regulation Of Cell Population Proliferation Cellular Defense Response Membrane Raft Distribution Cell Surface Membrane Raft Localization Leukocyte Differentiation Coreceptor Activity Leukocyte Cell-cell Adhesion Positive Regulation Of Immune System Process Presynaptic Membrane Assembly Cell Surface Receptor Signaling Pathway Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Presynaptic Membrane Organization Regulation Of Adaptive Immune Response Protein Kinase Binding Positive Regulation Of Intracellular Signal Transduction Negative Thymic T Cell Selection Positive Regulation Of Signal Transduction Negative T Cell Selection Regulation Of Cytokine Production Cell-cell Adhesion Immune Response Signal Transduction Positive Regulation Of Gene Expression Positive Regulation Of Multicellular Organismal Process Lymphocyte Differentiation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of T Cell Mediated Immunity Dendritic Spine Morphogenesis Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of T Cell Proliferation T Cell Receptor Complex T Cell Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production
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