LGALS1 and VPREB1

Number of citations of the paper that reports this interaction (PubMedID 12271131)
41

Data Source:
HPRD (in vitro, in vivo)

		LGALS1	VPREB1
Description		galectin 1	V-set pre-B cell surrogate light chain 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen Cytosol Plasma Membrane Extracellular Matrix Extracellular Exosome Galectin Complex	Extracellular Region Endoplasmic Reticulum Immunoglobulin Complex
	Molecular Function	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Laminin Binding Receptor Ligand Activity
	Biological Process	Plasma Cell Differentiation Apoptotic Process Signal Transduction T Cell Costimulation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of Inflammatory Response Cell-cell Adhesion Negative Regulation Of T-helper 17 Cell Lineage Commitment Positive Regulation Of Dendritic Cell Differentiation	Immune Response
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Cell surface interactions at the vascular wall
Drugs		Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol OTX-008
Diseases
GWAS		Fat distribution (HIV) ( 21897333)	Diastolic blood pressure ( 29208002) Periodontitis (PAL4Q3) ( 24024966) Response to selective serotonin reuptake inhibitors in depression ( 27622933)
Interacting Genes		17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1	3 interacting genes: IGHM LGALS1 VPREB3
Entrez ID		3956	7441
HPRD ID		01040	05505
Ensembl ID		ENSG00000100097	ENSG00000169575
Uniprot IDs		A0A384MR27 P09382	P12018
PDB IDs		1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83 6M5Y 7LTA 7NML 8B0W 8B0Z 8OJP 8R74 8RDC	2H32 2H3N 3BJ9
Enriched GO Terms of Interacting Partners?		External Side Of Plasma Membrane Lymphocyte Activation T Cell Activation Leukocyte Activation Cell Adhesion Cell Activation Immune System Process T Cell Selection Rhythmic Synaptic Transmission Signaling Receptor Activity Heterotypic Cell-cell Adhesion Positive Regulation Of Cytokine Production Mononuclear Cell Differentiation Positive Regulation Of Cell Population Proliferation Cellular Defense Response Membrane Raft Distribution Cell Surface Membrane Raft Localization Leukocyte Differentiation Coreceptor Activity Leukocyte Cell-cell Adhesion Positive Regulation Of Immune System Process Presynaptic Membrane Assembly Cell Surface Receptor Signaling Pathway Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Presynaptic Membrane Organization Regulation Of Adaptive Immune Response Protein Kinase Binding Positive Regulation Of Intracellular Signal Transduction Negative Thymic T Cell Selection Positive Regulation Of Signal Transduction Negative T Cell Selection Regulation Of Cytokine Production Cell-cell Adhesion Immune Response Signal Transduction Positive Regulation Of Gene Expression Positive Regulation Of Multicellular Organismal Process Lymphocyte Differentiation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of T Cell Mediated Immunity Dendritic Spine Morphogenesis Cytoplasmic Side Of Plasma Membrane Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of T Cell Proliferation T Cell Receptor Complex T Cell Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production	Immunoglobulin Complex Hexameric IgM Immunoglobulin Complex Pentameric IgM Immunoglobulin Complex Lactose Binding Galectin Complex IgM B Cell Receptor Complex IgM Immunoglobulin Complex Pre-B Cell Allelic Exclusion Positive Regulation Of Dendritic Cell Differentiation Plasma Cell Differentiation Immune System Process Negative Regulation Of T-helper 17 Cell Lineage Commitment Immunoglobulin Receptor Binding Extracellular Region Negative Regulation Of Cell Fate Commitment Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper 17 Type Immune Response Negative Regulation Of T-helper 17 Cell Differentiation Regulation Of Dendritic Cell Differentiation Peptidoglycan Binding Laminin Binding Regulation Of Viral Entry Into Host Cell Negative Regulation Of T-helper Cell Differentiation Positive Regulation Of Viral Life Cycle Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Mature B Cell Differentiation Involved In Immune Response Regulation Of T-helper 17 Cell Differentiation Negative Regulation Of Alpha-beta T Cell Differentiation Phosphatidylcholine Binding Myoblast Differentiation Mature B Cell Differentiation Antigen Binding Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of T-helper 17 Type Immune Response T Cell Costimulation Regulation Of Cell Fate Commitment B Cell Receptor Signaling Pathway Regulation Of Immune Response Negative Regulation Of T Cell Differentiation Regulation Of T-helper Cell Differentiation Negative Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Immune System Process Antibacterial Humoral Response Negative Regulation Of Lymphocyte Differentiation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Viral Process B Cell Activation Involved In Immune Response
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?