MTG1 and STX2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTG1	STX2
Description		mitochondrial ribosome associated GTPase 1	syntaxin 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Ribosome Membrane	Extracellular Space Plasma Membrane Endomembrane System Membrane Basolateral Plasma Membrane Lamellipodium SNARE Complex Protein-containing Complex Intracellular Membrane-bounded Organelle Presynaptic Active Zone Membrane
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	SNARE Binding Structural Molecule Activity SNAP Receptor Activity Protein Binding Identical Protein Binding Calcium-dependent Protein Binding
	Biological Process	Regulation Of Translation Regulation Of Respiratory System Process Regulation Of Mitochondrial Translation Mitochondrial Large Ribosomal Subunit Assembly	Intracellular Protein Transport Exocytosis Signal Transduction Acrosome Reaction Ectoderm Development Animal Organ Morphogenesis Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress Vesicle Docking Cornified Envelope Assembly
Pathways
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 24871463)	Initial pursuit acceleration in psychotic disorders ( 29064472) Metabolite levels ( 23823483) Plasma plasminogen activator levels ( 24578379) vWF levels ( 30586737)
Interacting Genes		10 interacting genes: APP DOCK8 ERICH1 KRT37 LRRK1 PICK1 PRNP RBFOX2 STRN4 STX2	65 interacting genes: AARD ABI3 ANKRD46 APOL2 BET1 BLOC1S2 CD53 CDC23 CERT1 CPLX2 CTSA CYBC1 EBAG9 ENTPD3 FGA GET1 GIMAP5 MIP MRPL11 MTG1 NAPB NINJ2 PCGF2 PLN PLPP4 RMDN3 RNF4 RTP2 SEC22A SEC22B SERP1 SLC18A1 SNAP25 SNAP29 SNCA STRIT1 STX12 STX16 STX1A STX1B STX3 STX4 STX5 STX6 STX7 STX8 STXBP1 STXBP2 STXBP5L SYT1 SYT4 SYT7 TMEM120A TMEM120B TSPAN8 UBE2I UNC13B VAMP2 VAMP3 VAMP5 VAPB VTI1B ZCCHC12 ZFPL1 ZNF785
Entrez ID		92170	2054
HPRD ID		11602	11816
Ensembl ID		ENSG00000148824	ENSG00000111450
Uniprot IDs		Q9BT17	A0A994J5V9 A0A994J840 P32856
PDB IDs		7O9K 7O9M 7PD3 8PK0 8QSJ
Enriched GO Terms of Interacting Partners?		Neuron Projection Organization Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Response To Copper Ion Molecular Function Activator Activity Positive Regulation Of Receptor Internalization Response To Copper Ion Regulation Of Synaptic Plasticity Positive Regulation Of T Cell Migration Dendritic Spine Organization Postsynapse Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Lymphocyte Migration Postsynapse Organization Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Cellular Response To Amyloid-beta Regulation Of T Cell Migration Glial Cell Development Type 8 Metabotropic Glutamate Receptor Binding Memory T Cell Proliferation Myeloid Cell Development Regulation Of Lymphocyte Migration Cellular Component Maintenance Positive Regulation Of Neuron Apoptotic Process G Protein-coupled Receptor Binding Regulation Of Receptor Internalization Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Calcium-mediated Signaling Positive Regulation Of Mononuclear Cell Migration Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production	SNAP Receptor Activity SNARE Complex Organelle Localization By Membrane Tethering SNARE Binding Membrane Docking Vesicle Docking Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion Vesicle Organization Membrane Organization Organelle Localization Syntaxin Binding Vesicle-mediated Transport Establishment Of Localization In Cell Synaptic Vesicle Exocytosis Exocytosis Calcium-ion Regulated Exocytosis Cellular Localization Syntaxin-1 Binding Secretion By Cell Regulated Exocytosis Vesicle Docking Involved In Exocytosis Vesicle-mediated Transport In Synapse Neurotransmitter Transport Calcium Ion-regulated Exocytosis Of Neurotransmitter Establishment Of Protein Localization Intracellular Transport Protein Transport Secretion Endomembrane System Signal Release SNARE Complex Assembly Synaptic Vesicle Membrane Membrane Regulation Of Exocytosis Regulation Of Secretion By Cell Regulation Of Synaptic Vesicle Priming Regulation Of Secretion Positive Regulation Of Exocytosis Intracellular Protein Transport Vesicle Intracellular Protein Localization Synaptic Vesicle Neuronal Dense Core Vesicle Exocytosis Regulation Of Vesicle Fusion Positive Regulation Of Synaptic Transmission Synaptic Vesicle Priming Positive Regulation Of Calcium Ion-dependent Exocytosis
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