MTG1 and KRT37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MTG1	KRT37
Description		mitochondrial ribosome associated GTPase 1	keratin 37
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Ribosome Membrane	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Regulation Of Translation Regulation Of Respiratory System Process Regulation Of Mitochondrial Translation Mitochondrial Large Ribosomal Subunit Assembly	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Systemic lupus erythematosus ( 24871463)	Squamous cell lung carcinoma ( 28604730)
Interacting Genes		10 interacting genes: APP DOCK8 ERICH1 KRT37 LRRK1 PICK1 PRNP RBFOX2 STRN4 STX2	47 interacting genes: AGXT AQP1 BCAS2 BFSP2 C21orf58 CCDC196 CLCNKA COL8A1 DES FAM110A FBXW5 GNG13 HAPLN2 HGS HOXA1 HSF4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT83 KRT85 KRT86 MTG1 NUFIP2 OIP5 OTX1 PIN1 PKN1 PSMA1 SMARCD1 SMARCE1 TBC1D21 TXLNB USHBP1
Entrez ID		92170	8688
HPRD ID		11602	05175
Ensembl ID		ENSG00000148824	ENSG00000108417
Uniprot IDs		Q9BT17	O76014
PDB IDs		7O9K 7O9M 7PD3 8PK0 8QSJ
Enriched GO Terms of Interacting Partners?		Neuron Projection Organization Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Dendritic Spine Maintenance Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Response To Copper Ion Molecular Function Activator Activity Positive Regulation Of Receptor Internalization Response To Copper Ion Regulation Of Synaptic Plasticity Positive Regulation Of T Cell Migration Dendritic Spine Organization Postsynapse Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Lymphocyte Migration Postsynapse Organization Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Synapse Organization Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Cellular Response To Amyloid-beta Regulation Of T Cell Migration Glial Cell Development Type 8 Metabotropic Glutamate Receptor Binding Memory T Cell Proliferation Myeloid Cell Development Regulation Of Lymphocyte Migration Cellular Component Maintenance Positive Regulation Of Neuron Apoptotic Process G Protein-coupled Receptor Binding Regulation Of Receptor Internalization Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Regulation Of Calcium-mediated Signaling Positive Regulation Of Mononuclear Cell Migration Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratinization Keratin Filament Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Extracellular Exosome Epidermis Development Structural Constituent Of Cytoskeleton Intermediate Filament Cytoskeleton Cytosol Developmental Process Cornified Envelope Brahma Complex NpBAF Complex Tissue Development RSC-type Complex NBAF Complex Protein Binding Peptide Cross-linking
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