RIPPLY1 and PLAGL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RIPPLY1	PLAGL2
Description		ripply transcriptional repressor 1	PLAG1 like zinc finger 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Somite Specification Embryonic Pattern Specification Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Post-embryonic Development Chylomicron Assembly Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)
Interacting Genes		44 interacting genes: AVPI1 BEND7 CFAP58 CTNNA3 DCAF15 DIRAS2 FHL2 GRAPL GRHL3 H3-4 HAND2 HDAC7 IRAK1BP1 KRT34 MCCD1 MDFI MED19 MEOX2 NDUFB7 PATZ1 PBX4 PFDN5 PLAGL2 PRR20A PRR20B PRR20C PRR20D PRR20E PTTG2 RBPMS REL RHOH RNF144B SAPCD1 THAP1 TRAF1 TRAF2 TRAF3 USP6 VAC14 VGLL1 ZMYND12 ZNF620 ZNF784	45 interacting genes: ANKRD11 ARID5A BCAS2 CATSPER1 CCDC120 CTNNA3 DAPP1 DHX57 DVL3 FAM161B FAM83A FAM90A1 GADD45G GEM GLYCTK GPATCH2L GYS1 INO80B IRX2 KANK2 MAD2L2 MAPK1 MORN4 NOS1AP OIP5 OLIG3 PAX9 PHC2 PIN1 PLAC8 PRR35 RCHY1 RHOBTB3 RIPPLY1 SAMD11 SEPHS1 SMARCD1 TEKT3 TEKT4 TRAF4 TRIM41 VEZF1 YPEL5 ZNF564 ZNF581
Entrez ID		92129	5326
HPRD ID			05333
Ensembl ID		ENSG00000147223	ENSG00000126003
Uniprot IDs		Q0D2K3	Q9UPG8
PDB IDs
Enriched GO Terms of Interacting Partners?		Signaling Adaptor Activity Thioesterase Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Tumor Necrosis Factor Receptor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Sequence-specific DNA Binding CD40 Receptor Complex Tumor Necrosis Factor-mediated Signaling Pathway
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