NEK9 and SUPT16H

Number of citations of the paper that reports this interaction (PMID 14660563)
14

Data Source:
HPRD (in vivo)

		NEK9	SUPT16H
Gene Name		NIMA-related kinase 9	suppressor of Ty 16 homolog (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Mitotic Nuclear Envelope Disassembly Cell Division	DNA Replication DNA Repair Nucleosome Disassembly Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription
Pathways		Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase	Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BICD2 MBP NEK6 NEK7 RAN SSRP1 SUPT16H	10 interactors: GTF2E2 H2AFX H3F3A HIST1H2AI MCM3 MCM4 NEK9 PARP1 SREK1 SRPK2
Entrez ID		91754	11198
HPRD ID		11386	16088
Ensembl ID		ENSG00000119638	ENSG00000092201
Uniprot IDs		Q6PKF2 Q8TD19	Q9Y5B9
PDB IDs		3ZKE 3ZKF
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Organization Spindle Organization Organelle Organization Microtubule-based Process Positive Regulation Of Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Cytoskeleton Organization Regulation Of Viral Transcription Cell Division Positive Regulation Of Viral Process Spindle Assembly DNA-templated Transcription, Elongation Viral Process Cytokinesis Ribosomal Small Subunit Export From Nucleus Defense Response To Nematode Minus-end-directed Organelle Transport Along Microtubule Regulation Of Viral Process Cellular Response To DNA Damage Stimulus Response To Nematode Ribosomal Large Subunit Export From Nucleus Cell Cycle Process Ribosomal Subunit Export From Nucleus DNA Metabolic Process DNA Replication Mitotic Nuclear Division Microtubule Anchoring At Microtubule Organizing Center Cellular Protein Complex Localization Nucleosome Disassembly Negative Regulation Of Interleukin-10 Production Cell Cycle Protein Complex Localization Regulation Of Mitotic Cell Cycle Positive Regulation Of Interleukin-4 Production Positive Regulation Of Macromolecule Biosynthetic Process Response To Mercury Ion Regulation Of Cellular Senescence Cellular Response To Stress Positive Regulation Of Gene Expression Organelle Assembly Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-4 Production G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Response To Stress Substantia Nigra Development Protein Export From Nucleus Androgen Receptor Signaling Pathway	DNA Conformation Change Chromosome Organization DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Heterocycle Metabolic Process DNA Replication Initiation Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nuclear Speck Organization DNA Duplex Unwinding DNA Geometric Change Cell Cycle Process DNA-dependent DNA Replication Nucleosome Assembly Nucleus Organization Regulation Of Growth Rate Protein Poly-ADP-ribosylation Chromatin Assembly Nucleosome Organization Cell Cycle Double-strand Break Repair Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecular Complex Assembly Protein-DNA Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process DNA Packaging Cellular Metabolic Process Mitotic Cell Cycle DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription Regulatory Region DNA Binding DNA-templated Transcription, Initiation Protein Autoprocessing DNA Unwinding Involved In DNA Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Methylation On Cytosine DNA Replication Positive Regulation Of SMAD Protein Import Into Nucleus Chromatin Silencing At RDNA Regulation Of SMAD Protein Import Into Nucleus Gene Expression Macrophage Differentiation RNA Splicing Positive Regulation Of Viral Genome Replication
Tagcloud ?		adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence	altering breaks checkpoint chemo conjunction cooperate disassembly dsb dsbs dynamic facilitates fact gammah2ax h2ax h2b h2bub1 h3k56ac homolog mechanistic monoubiquitination phenocopied proper pursuing rational repair rnf40 strand timely ty
Tagcloud (Difference) ?		adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence	altering breaks checkpoint chemo conjunction cooperate disassembly dsb dsbs dynamic facilitates fact gammah2ax h2ax h2b h2bub1 h3k56ac homolog mechanistic monoubiquitination phenocopied proper pursuing rational repair rnf40 strand timely ty
Tagcloud (Intersection) ?