NEK9 and NEK7

Number of citations of the paper that reports this interaction (PMID 20562859)
242

Data Source:
BioGRID (enzymatic study, affinity chromatography technology)
HPRD (in vivo, in vitro)

		NEK9	NEK7
Gene Name		NIMA-related kinase 9	NIMA-related kinase 7
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol	Spindle Pole Nucleoplasm Cytoplasm Microtubule Organizing Center Microtubule
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Metal Ion Binding	Protein Serine/threonine Kinase Activity ATP Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Protein Phosphorylation Mitotic Nuclear Division Mitotic Nuclear Envelope Disassembly Cell Division	Cytokinesis Protein Phosphorylation Regulation Of Mitotic Cell Cycle Regulation Of Signal Transduction Spindle Assembly
Pathways		Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase	Mitotic Prophase Activation of NIMA Kinases NEK9, NEK6, NEK7 Nuclear Envelope Breakdown Nuclear Pore Complex (NPC) Disassembly Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BICD2 MBP NEK6 NEK7 RAN SSRP1 SUPT16H	1 interactors: NEK9
Entrez ID		91754	140609
HPRD ID		11386	06027
Ensembl ID		ENSG00000119638	ENSG00000151414
Uniprot IDs		Q6PKF2 Q8TD19	B2R8K8 Q8TDX7
PDB IDs		3ZKE 3ZKF	2WQM 2WQN
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Organization Spindle Organization Organelle Organization Microtubule-based Process Positive Regulation Of Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Cytoskeleton Organization Regulation Of Viral Transcription Cell Division Positive Regulation Of Viral Process Spindle Assembly DNA-templated Transcription, Elongation Viral Process Cytokinesis Ribosomal Small Subunit Export From Nucleus Defense Response To Nematode Minus-end-directed Organelle Transport Along Microtubule Regulation Of Viral Process Cellular Response To DNA Damage Stimulus Response To Nematode Ribosomal Large Subunit Export From Nucleus Cell Cycle Process Ribosomal Subunit Export From Nucleus DNA Metabolic Process DNA Replication Mitotic Nuclear Division Microtubule Anchoring At Microtubule Organizing Center Cellular Protein Complex Localization Nucleosome Disassembly Negative Regulation Of Interleukin-10 Production Cell Cycle Protein Complex Localization Regulation Of Mitotic Cell Cycle Positive Regulation Of Interleukin-4 Production Positive Regulation Of Macromolecule Biosynthetic Process Response To Mercury Ion Regulation Of Cellular Senescence Cellular Response To Stress Positive Regulation Of Gene Expression Organelle Assembly Intracellular Transport Of Virus Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Interleukin-4 Production G2 DNA Damage Checkpoint Mitotic Nuclear Envelope Disassembly Response To Stress Substantia Nigra Development Protein Export From Nucleus Androgen Receptor Signaling Pathway	Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Nuclear Envelope Organization Nucleus Organization
Tagcloud ?		adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network nima p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence	chip decade delay dimethylation dysplastic elucidated h3k36me2 h3k36me3 hirschhorn hmts ihc immunoblot immunocytochemical knockdown locoregionally malignancy methyltransferase methyltransferases neck nima nsd oncogenic player possesses scchn suboptimal urgently whsc1 wolf
Tagcloud (Difference) ?		adenocarcinoma broad crucial cycle deficient depletion elimination encoding exhibited g1 ideal inactivated lacking microrna network p53 poorer predominantly prognoses promotes regulator regulators represents repression resultant screen selectively senescence	chip decade delay dimethylation dysplastic elucidated h3k36me2 h3k36me3 hirschhorn hmts ihc immunoblot immunocytochemical knockdown locoregionally malignancy methyltransferase methyltransferases neck nsd oncogenic player possesses scchn suboptimal urgently whsc1 wolf
Tagcloud (Intersection) ?		nima