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SUPT16H and HIST1H2AI
Number of citations of the paper that reports this interaction (PMID
18206970
)
71
Data Source:
HPRD
(in vitro)
SUPT16H
HIST1H2AI
Gene Name
suppressor of Ty 16 homolog (S. cerevisiae)
histone cluster 1, H2ai
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Chromosome
Nucleosome
Nucleus
Extracellular Vesicular Exosome
Molecular Function
Protein Binding
Poly(A) RNA Binding
DNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
Biological Process
DNA Replication
DNA Repair
Nucleosome Disassembly
Transcription From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
Gene Expression
Viral Process
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Viral Transcription
Biological_process
Pathways
Formation of HIV-1 elongation complex containing HIV-1 Tat
RNA Polymerase II Transcription
HIV Infection
Tat-mediated elongation of the HIV-1 transcript
Tat-mediated HIV elongation arrest and recovery
RNA Polymerase II Pre-transcription Events
Late Phase of HIV Life Cycle
Pausing and recovery of Tat-mediated HIV elongation
Formation of RNA Pol II elongation complex
HIV elongation arrest and recovery
HIV Life Cycle
Pausing and recovery of HIV elongation
Formation of HIV elongation complex in the absence of HIV Tat
HIV Transcription Elongation
Transcription of the HIV genome
RNA Polymerase II Transcription Elongation
Chromatin modifying enzymes
HDACs deacetylate histones
Chromatin organization
HATs acetylate histones
RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions
10 interactors:
GTF2E2
H2AFX
H3F3A
HIST1H2AI
MCM3
MCM4
NEK9
PARP1
SREK1
SRPK2
2 interactors:
SUPT16H
UBC
Entrez ID
11198
8329
HPRD ID
16088
04153
Ensembl ID
ENSG00000092201
ENSG00000196747
Uniprot IDs
Q9Y5B9
A4FTV9
P0C0S8
PDB IDs
Enriched GO Terms of Interacting Partners
?
DNA Conformation Change
Chromosome Organization
DNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Organelle Organization
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Heterocycle Metabolic Process
DNA Replication Initiation
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Nuclear Speck Organization
DNA Duplex Unwinding
DNA Geometric Change
Cell Cycle Process
DNA-dependent DNA Replication
Nucleosome Assembly
Nucleus Organization
Regulation Of Growth Rate
Protein Poly-ADP-ribosylation
Chromatin Assembly
Nucleosome Organization
Cell Cycle
Double-strand Break Repair
Chromatin Assembly Or Disassembly
G1/S Transition Of Mitotic Cell Cycle
Cellular Macromolecular Complex Assembly
Protein-DNA Complex Assembly
Transcription Initiation From RNA Polymerase II Promoter
Mitotic Cell Cycle Process
DNA Packaging
Cellular Metabolic Process
Mitotic Cell Cycle
DNA Damage Response, Detection Of DNA Damage
Positive Regulation Of Transcription Regulatory Region DNA Binding
DNA-templated Transcription, Initiation
Protein Autoprocessing
DNA Unwinding Involved In DNA Replication
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Methylation On Cytosine
DNA Replication
Positive Regulation Of SMAD Protein Import Into Nucleus
Chromatin Silencing At RDNA
Regulation Of SMAD Protein Import Into Nucleus
Gene Expression
Macrophage Differentiation
RNA Splicing
Positive Regulation Of Viral Genome Replication
Viral Process
DNA Repair
Viral Protein Processing
Nucleosome Disassembly
Cellular Response To DNA Damage Stimulus
Transcription From RNA Polymerase II Promoter
Notch Receptor Processing
Virion Assembly
DNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Glycogen Biosynthetic Process
Intracellular Transport Of Virus
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription, DNA-templated
Cellular Polysaccharide Biosynthetic Process
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Polysaccharide Biosynthetic Process
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Viral Transcription
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Negative Regulation Of ERBB Signaling Pathway
Positive Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Stress
Positive Regulation Of Gene Expression
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Toll-like Receptor 5 Signaling Pathway
Regulation Of DNA-templated Transcription, Elongation
Toll-like Receptor 10 Signaling Pathway
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of DNA-templated Transcription In Response To Stress
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
I-kappaB Kinase/NF-kappaB Signaling
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Toll-like Receptor 2 Signaling Pathway
Signal Transduction Involved In DNA Damage Checkpoint
Toll-like Receptor 9 Signaling Pathway
Signal Transduction Involved In Cell Cycle Checkpoint
Glycogen Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Viral Transcription
Tagcloud
?
altering
breaks
checkpoint
chemo
conjunction
cooperate
disassembly
dsb
dsbs
dynamic
facilitates
fact
gammah2ax
h2ax
h2b
h2bub1
h3k56ac
homolog
mechanistic
monoubiquitination
phenocopied
proper
pursuing
rational
repair
rnf40
strand
timely
ty
Tagcloud (Difference)
?
altering
breaks
checkpoint
chemo
conjunction
cooperate
disassembly
dsb
dsbs
dynamic
facilitates
fact
gammah2ax
h2ax
h2b
h2bub1
h3k56ac
homolog
mechanistic
monoubiquitination
phenocopied
proper
pursuing
rational
repair
rnf40
strand
timely
ty
Tagcloud (Intersection)
?