SUPT16H

Gene Name		suppressor of Ty 16 homolog (S. cerevisiae)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding Poly(A) RNA Binding
	Biological Process	DNA Replication DNA Repair Nucleosome Disassembly Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription
Pathways		Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle Pausing and recovery of Tat-mediated HIV elongation Formation of RNA Pol II elongation complex HIV elongation arrest and recovery HIV Life Cycle Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat HIV Transcription Elongation Transcription of the HIV genome RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: GTF2E2 H2AFX H3F3A HIST1H2AI MCM3 MCM4 NEK9 PARP1 SREK1 SRPK2
Entrez ID		11198
HPRD ID		16088
Ensembl ID		ENSG00000092201
Uniprot IDs		Q9Y5B9
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Conformation Change Chromosome Organization DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Organelle Organization DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Heterocycle Metabolic Process DNA Replication Initiation Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nuclear Speck Organization DNA Duplex Unwinding DNA Geometric Change Cell Cycle Process DNA-dependent DNA Replication Nucleosome Assembly Nucleus Organization Regulation Of Growth Rate Protein Poly-ADP-ribosylation Chromatin Assembly Nucleosome Organization Cell Cycle Double-strand Break Repair Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Cellular Macromolecular Complex Assembly Protein-DNA Complex Assembly Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Process DNA Packaging Cellular Metabolic Process Mitotic Cell Cycle DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription Regulatory Region DNA Binding DNA-templated Transcription, Initiation Protein Autoprocessing DNA Unwinding Involved In DNA Replication Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Methylation On Cytosine DNA Replication Positive Regulation Of SMAD Protein Import Into Nucleus Chromatin Silencing At RDNA Regulation Of SMAD Protein Import Into Nucleus Gene Expression Macrophage Differentiation RNA Splicing Positive Regulation Of Viral Genome Replication
Tagcloud ?		altering breaks checkpoint chemo conjunction cooperate disassembly dsb dsbs dynamic facilitates fact gammah2ax h2ax h2b h2bub1 h3k56ac homolog mechanistic monoubiquitination phenocopied proper pursuing rational repair rnf40 strand timely ty