CBFA2T2 and PRDM14

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid, two hybrid)

		CBFA2T2	PRDM14
Gene Name		core-binding factor, runt domain, alpha subunit 2; translocated to, 2	PR domain containing 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	DNA Binding Protein Binding Methyltransferase Activity Metal Ion Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Cell Morphogenesis Cell Fate Specification Inner Cell Mass Cell Fate Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated Germ Cell Development Fertilization Germ-line Stem Cell Maintenance Histone H3-R26 Methylation Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of DNA Methylation Homeostasis Of Number Of Cells Within A Tissue
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS			Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		23 interactors: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 PDP1 PRDM14 RERE RUNX1 SIN3A TAL2 TCP1 WDYHV1 ZNF652	19 interactors: AKAP9 ATPAF2 BEX2 CBFA2T2 CDCA7L DGCR6 EIF4E2 GPATCH2L HEXIM2 HSPB7 ID3 MIA3 PRKAB2 PSMA1 RAD51D RCOR3 RUNX1T1 TEKT4 TTC32
Entrez ID		9139	63978
HPRD ID		04721	11457
Ensembl ID		ENSG00000078699	ENSG00000147596
Uniprot IDs		O43439	Q9GZV8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Biosynthetic Process Organ Development Definitive Hemopoiesis Central Nervous System Development Developmental Process System Development Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Forebrain Development DNA-templated Transcription, Initiation Metabolic Process Embryo Development Negative Regulation Of Cellular Metabolic Process Myeloid Cell Differentiation Thalamus Development In Utero Embryonic Development Nervous System Development Positive Regulation Of Mitotic Cell Cycle
Tagcloud ?			adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4
Tagcloud (Difference) ?			adam9 aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 qiagen salsa top2a traf4
Tagcloud (Intersection) ?