ID3 and ZNF626

Number of citations of the paper that reports this interaction (PubMedID 18255255)
0

Data Source:
BioGRID (two hybrid)

		ID3	ZNF626
Description		inhibitor of DNA binding 3	zinc finger protein 626
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding BHLH Transcription Factor Binding Protein Dimerization Activity Transcription Regulator Inhibitor Activity Leptomycin B Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Metanephros Development Regulation Of DNA Replication Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Leptomycin B	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		NGF-stimulated transcription	Generic Transcription Pathway
Drugs
Diseases
GWAS			Cognitive decline (age-related) ( 28078323) Night sleep phenotypes ( 27126917) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		49 interacting genes: ADD1 ANKS1A ATF3 BOLA2 BOLA2B C22orf39 CBFA2T2 CDK2 CNOT3 CREB5 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 FRS3 GATA4 GNB2 GTF2A1L GUCD1 HES1 HOXA1 ID4 IFI16 IKBKG KAT5 KRTAP26-1 LMO4 MLX MSGN1 MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SDCBP SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626	2 interacting genes: FHL2 ID3
Entrez ID		3399	199777
HPRD ID		02608	15881
Ensembl ID		ENSG00000117318	ENSG00000188171
Uniprot IDs		Q02535	B9EK70 Q68DY1
PDB IDs		2LFH
Enriched GO Terms of Interacting Partners?		Protein Dimerization Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding E-box Binding Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Cellular Developmental Process Nucleus Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Cell Differentiation Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Skeletal Muscle Cell Differentiation Negative Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Skeletal Muscle Fiber Development Regulation Of Skeletal Muscle Fiber Development Nucleoplasm Positive Regulation Of Metabolic Process Transcription Regulator Complex Cell Fate Commitment Negative Regulation Of Macromolecule Biosynthetic Process Muscle Cell Fate Commitment Positive Regulation Of Macromolecule Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Biosynthetic Process Positive Regulation Of Myoblast Differentiation Positive Regulation Of Skeletal Muscle Tissue Development Positive Regulation Of Striated Muscle Tissue Development	BHLH Transcription Factor Binding Cellular Response To Leptomycin B Leptomycin B Binding Transcription Corepressor Activity Atrial Cardiac Muscle Cell Development Ventricular Cardiac Muscle Cell Development Notochord Development Negative Regulation Of Calcineurin-NFAT Signaling Cascade Heart Trabecula Formation Negative Regulation Of Calcium-mediated Signaling Transcription Factor Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Myoblast Differentiation Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Cardiac Muscle Cell Development Metanephros Development Transcription Regulator Inhibitor Activity Cellular Response To Fatty Acid Cardiac Cell Development Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Programmed Cell Death Negative Regulation Of RNA Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Osteoblast Differentiation Response To Fatty Acid Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Striated Muscle Cell Development Regulation Of Myoblast Differentiation Muscle Cell Development Regulation Of Calcium-mediated Signaling Odontogenesis Regulation Of DNA Replication
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