HN1L and EGR2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		HN1L	EGR2
Gene Name		hematological and neurological expressed 1-like	early growth response 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleus Cytoplasm
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Activating Transcription Factor Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Ligase Activity Ubiquitin Protein Ligase Binding Transcription Regulatory Region DNA Binding Metal Ion Binding HMG Box Domain Binding
	Biological Process		Transcription From RNA Polymerase II Promoter Protein Export From Nucleus Brain Development Peripheral Nervous System Development Learning Or Memory Rhythmic Behavior Motor Neuron Axon Guidance Schwann Cell Differentiation Protein Sumoylation Facial Nerve Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation Regulation Of Ossification Response To Insulin Brain Segmentation Skeletal Muscle Cell Differentiation Myelination Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Neuronal Synaptic Plasticity Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus
Pathways			Transcriptional regulation of white adipocyte differentiation
Drugs
Diseases
GWAS			Atopic dermatitis ( 23042114) Ewing sarcoma ( 22327514) Temperament ( 22832960)
Protein-Protein Interactions		7 interactors: CNTFR CSNK1D EGR2 RASA4 SEPT2 SLC25A20 XRCC6	16 interactors: ACP5 BPGM HCFC1 HN1L MED31 NAB2 NDUFS2 NFATC1 RBM15B RIMKLB RPL7L1 SOX10 SOX8 SRA1 UBE2I WWP2
Entrez ID		90861	1959
HPRD ID		12674	00551
Ensembl ID		ENSG00000206053	ENSG00000122877
Uniprot IDs		A6NGP5 Q9H910	P11161
PDB IDs
Enriched GO Terms of Interacting Partners?		Rhombomere 5 Formation Rhombomere 3 Formation Rhombomere 3 Morphogenesis Skeletal Muscle Organ Development Brain Segmentation Cellular Hyperosmotic Salinity Response Rhombomere 3 Development Rhombomere 5 Development Regulation Of L-glutamate Transport Rhombomere Morphogenesis Ciliary Neurotrophic Factor-mediated Signaling Pathway Cellular Response To X-ray Establishment Of Integrated Proviral Latency Nervous System Development Carnitine Shuttle Cellular Response To Stimulus Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Muscle Organ Development Rhombomere Development Carnitine Transmembrane Transport Rhythmic Process Cellular Response To Salt Stress Facial Nerve Structural Organization Carnitine Transport Facial Nerve Morphogenesis DNA Ligation Brainstem Development Quaternary Ammonium Group Transport Rhythmic Behavior Parasympathetic Nervous System Development	Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Enteric Nervous System Development Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Peripheral Nervous System Development Regulation Of Transcription From RNA Polymerase II Promoter Mesenchymal Cell Development Heterocycle Metabolic Process Negative Regulation Of Gene Expression Regulation Of Gene Expression Mesenchymal Cell Differentiation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Glial Cell Differentiation Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Mesenchyme Development Viral Process Gene Expression Nucleobase-containing Compound Metabolic Process Autonomic Nervous System Development Cellular Macromolecule Biosynthetic Process Gliogenesis Neural Crest Cell Migration Regulation Of Metabolic Process Stem Cell Development Macromolecule Biosynthetic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Gliogenesis Metabolic Process Positive Regulation Of SUMO Transferase Activity Neural Crest Cell Development Stem Cell Differentiation Oligodendrocyte Differentiation Neural Crest Cell Differentiation Retinal Rod Cell Differentiation Negative Regulation Of Superoxide Anion Generation Release From Viral Latency Regulation Of Gliogenesis Renal Vesicle Induction
Tagcloud ?			1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Difference) ?			1beta attraction ccl2 ccl7 cd40 chemokines csf1 cxcl10 dark dendrites elongation enforced exert homer1a ht22 microglia mononuclear movement nrem phagocytes profoundly sleep somnogeneic stimulate synapses tnf vicinity wake wakefulness
Tagcloud (Intersection) ?