JPT2 and CNTFR

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		JPT2	CNTFR
Description		Jupiter microtubule associated homolog 2	ciliary neurotrophic factor receptor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Ciliary Neurotrophic Factor Receptor Complex CNTFR-CLCF1 Complex Side Of Membrane
	Molecular Function	Protein Binding	Cytokine Receptor Activity Ciliary Neurotrophic Factor Receptor Activity Interleukin-11 Receptor Activity Signaling Receptor Binding Protein Binding Cytokine Binding Interleukin-11 Binding
	Biological Process	Regulation Of Calcium-mediated Signaling Endocytosis Involved In Viral Entry Into Host Cell	Suckling Behavior Brainstem Development Signal Transduction Nervous System Development Sex Differentiation Positive Regulation Of Cell Population Proliferation Interleukin-11-mediated Signaling Pathway Negative Regulation Of Neuron Apoptotic Process Skeletal Muscle Organ Development Ciliary Neurotrophic Factor-mediated Signaling Pathway Motor Neuron Apoptotic Process Negative Regulation Of Motor Neuron Apoptotic Process
Pathways			IL-6-type cytokine receptor ligand interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Physiological traits ( 31902109)
Interacting Genes		8 interacting genes: CDC42 CNTFR CSNK1D EGR2 RASA4 SEPTIN2 SLC25A20 XRCC6	9 interacting genes: APPBP2 CLCF1 CNTF CRLF1 IL6ST JPT2 KRTAP4-12 LIFR PLSCR1
Entrez ID		90861	1271
HPRD ID		12674	00348
Ensembl ID		ENSG00000206053	ENSG00000122756
Uniprot IDs		A6NGP5 Q9H910	P26992
PDB IDs			1UC6 8D74 8D7E 8D7H 8D7R
Enriched GO Terms of Interacting Partners?		Carnitine:O-acyl-L-carnitine Antiporter Activity O-acyl-L-carnitine Transmembrane Transporter Activity Cell Projection Assembly Plasma Membrane Bounded Cell Projection Organization Spindle Plasma Membrane Bounded Cell Projection Assembly Rhombomere 5 Structural Organization Rhombomere 3 Structural Organization Rhombomere 3 Formation Rhombomere 5 Formation O-acyl-L-carnitine Transmembrane Transport GBD Domain Binding Storage Vacuole Cell Projection Organization CNTFR-CLCF1 Complex Golgi Organization Endothelin Receptor Signaling Pathway Involved In Heart Process Ciliary Neurotrophic Factor Receptor Complex Rhombomere 3 Development Positive Regulation Of Schwann Cell Differentiation Brain Segmentation DNA End Binding Ku70:Ku80 Complex Carnitine Shuttle Apolipoprotein A-I Receptor Binding Neuropilin Signaling Pathway Interleukin-11 Receptor Activity Ciliary Neurotrophic Factor Receptor Activity Interleukin-11 Binding Regulation Of Schwann Cell Differentiation Ciliary Neurotrophic Factor-mediated Signaling Pathway Cellular Hyperosmotic Salinity Response DNA-dependent Protein Kinase Complex	Ciliary Neurotrophic Factor Receptor Binding Ciliary Neurotrophic Factor-mediated Signaling Pathway Cytokine-mediated Signaling Pathway Cell Surface Receptor Signaling Pathway Via STAT Leukemia Inhibitory Factor Receptor Activity CRLF-CLCF1 Complex Oncostatin-M Receptor Activity Negative Regulation Of Neuron Apoptotic Process Ciliary Neurotrophic Factor Receptor Activity Leukemia Inhibitory Factor Signaling Pathway Cytokine Binding Oncostatin-M-mediated Signaling Pathway Cytokine Receptor Activity Positive Regulation Of Cell Population Proliferation Cytokine Activity Interleukin-6 Receptor Binding Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Neuron Apoptotic Process Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Positive Regulation Of Leukocyte Proliferation Regulation Of Cell Population Proliferation Regulation Of Astrocyte Differentiation Receptor Complex Positive Regulation Of Glial Cell Differentiation Regulation Of Adaptive Immune Response Positive Regulation Of Gene Expression Cell Surface Receptor Signaling Pathway Growth Factor Binding Regulation Of Mononuclear Cell Proliferation Regulation Of Cell Activation Positive Regulation Of Immune Response Extracellular Region Regulation Of Leukocyte Proliferation Positive Regulation Of Dendritic Cell Dendrite Assembly Positive Regulation Of Gliogenesis Regulation Of Apoptotic Process Regulation Of Glial Cell Differentiation Regulation Of Programmed Cell Death Extracellular Space Positive Regulation Of Lymphocyte Activation External Side Of Plasma Membrane Interleukin-27 Receptor Activity Interleukin-6 Binding Interleukin-6 Receptor Activity Oncostatin-M Receptor Complex Lead Ion Binding
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