CTAG1A and ALOX15B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTAG1A	ALOX15B
Description		cancer/testis antigen 1A	arachidonate 15-lipoxygenase type B
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GO Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Membrane Extracellular Exosome Anchoring Junction
	Molecular Function	Protein Binding Identical Protein Binding	Iron Ion Binding Calcium Ion Binding Protein Binding Lipid Binding Linoleate 13S-lipoxygenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen Arachidonate 8(S)-lipoxygenase Activity Metal Ion Binding Arachidonate 15-lipoxygenase Activity Dioxygenase Activity Linoleate 9S-lipoxygenase Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Metabolic Process	Lipid Metabolic Process Phospholipid Metabolic Process Apoptotic Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Arachidonate Metabolic Process Lipoxygenase Pathway Negative Regulation Of Cell Migration Prostate Gland Development Regulation Of Epithelial Cell Differentiation Positive Regulation Of Chemokine Production Lipid Oxidation Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Linoleic Acid Metabolic Process Positive Regulation Of Keratinocyte Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Growth Hepoxilin Biosynthetic Process Endocannabinoid Signaling Pathway Cannabinoid Biosynthetic Process Lipoxin A4 Biosynthetic Process
Pathways			Synthesis of 15-eicosatetraenoic acid derivatives
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Childhood ALL/LBL (acute lymphoblastic leukemia/lymphoblastic lymphoma) treatment-related venous thromboembolism ( 32438682) Menarche (age at onset) ( 25231870) Metabolite levels ( 23823483)
Interacting Genes		76 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1B CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX	9 interacting genes: CTAG1A CTAG1B KCNF1 PPARG RARA RXRA TRAIP TRIM21 VMA22
Entrez ID		246100	247
HPRD ID		06607	04739
Ensembl ID		ENSG00000268651	ENSG00000179593
Uniprot IDs		P78358	O15296
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1	4NRE 7LAF 8VIY
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Skeletal Muscle Atrophy Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Regulation Of Protein Ubiquitination Cytoplasm Skeletal Muscle Adaptation Striated Muscle Atrophy Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Involved In Protein Catabolic Process	Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Lipoprotein Transport Nuclear Receptor Activity MRNA Transcription By RNA Polymerase II DNA Binding Domain Binding LBD Domain Binding MRNA Transcription Retinoic Acid-responsive Element Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System Peroxisome Proliferator Activated Receptor Signaling Pathway Nuclear Receptor-mediated Signaling Pathway Alpha-actinin Binding RNA Polymerase II Transcription Regulator Complex TRNA Threonylcarbamoyladenosine Metabolic Process Hormone-mediated Signaling Pathway Monocyte Differentiation Retinoic Acid Binding Identical Protein Binding Negative Regulation Of MiRNA Transcription Positive Regulation Of Cholesterol Efflux Peptide Binding Cellular Response To Low-density Lipoprotein Particle Stimulus Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Nucleic Acid Metabolic Process Positive Regulation Of Cholesterol Transport Cellular Response To Lipoprotein Particle Stimulus Intracellular Receptor Signaling Pathway Protein Catabolic Process Transcription Coregulator Binding Regulation Of Cholesterol Efflux Macromolecule Metabolic Process Positive Regulation Of Binding Transcription Cis-regulatory Region Binding RNA Metabolic Process Transcription By RNA Polymerase II Regulation Of Cholesterol Transport Sertoli Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of MiRNA Transcription Positive Regulation Of Lipid Transport Enzyme Binding Regulation Of MiRNA Metabolic Process Negative Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Negative Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Adiponectin Secretion Negative Regulation Of Innate Immune Response Negative Regulation Of Response To Cytokine Stimulus DNA-templated Transcription Response To Retinoic Acid Macromolecule Catabolic Process
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