CTAG1A and LAMTOR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CTAG1A	LAMTOR1
Description		cancer/testis antigen 1A	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
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GO Annotations	Cellular Component	Cytoplasm	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Membrane Raft Extracellular Exosome Ragulator Complex Ficolin-1-rich Granule Membrane FNIP-folliculin RagC/D GAP
	Molecular Function	Protein Binding Identical Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein-membrane Adaptor Activity GTPase Binding Molecular Adaptor Activity
	Biological Process	TRNA Threonylcarbamoyladenosine Metabolic Process	Autophagosome Assembly Regulation Of Cell Growth Regulation Of Receptor Recycling Cytoplasmic Translation Endosome Organization Lysosome Organization Intracellular Protein Localization Negative Regulation Of Autophagy Regulation Of Cholesterol Efflux Endosomal Transport Cellular Response To Nutrient Levels Positive Regulation Of TOR Signaling Lysosome Localization TORC1 Signaling Cholesterol Homeostasis Positive Regulation Of MAPK Cascade Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Regulation Of Cholesterol Import Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus Protein Localization To Membrane Positive Regulation Of Protein Localization To Lysosome Positive Regulation Of TORC1 Signaling
Pathways			Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Neutrophil degranulation Regulation of PTEN gene transcription CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle Amino acids regulate mTORC1
Drugs
Diseases
GWAS
Interacting Genes		76 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1B CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX	8 interacting genes: ABCF3 CAPN1 CCDC90B CTAG1A CTAG1B EEF1A1 NLRP3 TRIM14
Entrez ID		246100	55004
HPRD ID		06607	07933
Ensembl ID		ENSG00000268651	ENSG00000149357
Uniprot IDs		P78358	Q6IAA8
PDB IDs		1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1	5X6U 5X6V 5Y39 5Y3A 5YK3 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3 7T3A 7T3B 7T3C 7UX2 7UXC 7UXH 8DHB
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Post-translational Protein Targeting To Endoplasmic Reticulum Membrane TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteasomal Protein Catabolic Process Skeletal Muscle Atrophy Regulation Of Proteasomal Protein Catabolic Process Protein Targeting To ER Regulation Of Protein Ubiquitination Cytoplasm Skeletal Muscle Adaptation Striated Muscle Atrophy Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Proteolysis Involved In Protein Catabolic Process	TRNA Threonylcarbamoyladenosine Metabolic Process Molecular Adaptor Activity
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