PLOD3 and DPPA2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLOD3	DPPA2
Gene Name		procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	developmental pluripotency associated 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity	Chromatin Binding
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Cellular Protein Modification Process Protein Localization Neural Tube Development Extracellular Matrix Organization Collagen Fibril Organization Cellular Response To Hormone Stimulus Vasodilation Epidermis Morphogenesis Oxidation-reduction Process Lung Morphogenesis Basement Membrane Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Regulation Of Histone Methylation Lung-associated Mesenchyme Development Positive Regulation Of Stem Cell Proliferation
Pathways		Collagen formation Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS			Corneal astigmatism ( 23761726)
Protein-Protein Interactions		7 interactors: CCDC85B DPPA2 EFHC2 EHMT2 FAM153A RAB3IP RHOXF2	16 interactors: AP2M1 DPPA4 DVL2 DVL3 FXR2 MCM10 MOAP1 PBXIP1 PLOD3 SDCBP2 SETD5 SPOP U2AF2 VTA1 ZCCHC10 ZNF250
Entrez ID		8985	151871
HPRD ID		04347	13248
Ensembl ID		ENSG00000106397	ENSG00000163530
Uniprot IDs		O60568 Q9UG85	Q7Z7J5
PDB IDs
Enriched GO Terms of Interacting Partners?			Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Wnt Signaling Pathway, Planar Cell Polarity Pathway Cochlea Morphogenesis Non-canonical Wnt Signaling Pathway Cochlea Development Outflow Tract Morphogenesis Positive Regulation Of JUN Kinase Activity Regulation Of JUN Kinase Activity Intracellular Transport Canonical Wnt Signaling Pathway Cellular Localization Inner Ear Morphogenesis Convergent Extension Involved In Neural Plate Elongation Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Embryonic Development Protein Insertion Into Mitochondrial Membrane Basement Membrane Assembly Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of JNK Cascade Ear Morphogenesis Positive Regulation Of Stress-activated MAPK Cascade Non-canonical Wnt Signaling Pathway Via JNK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Non-canonical Wnt Signaling Pathway Via MAPK Cascade Convergent Extension Involved In Organogenesis Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Canonical Wnt Signaling Pathway Protein Localization Positive Regulation Of Wnt Signaling Pathway Regulation Of JNK Cascade Establishment Of Localization In Cell Positive Regulation Of Signal Transduction Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Neural Plate Morphogenesis Regulation Of Organ Morphogenesis Regulation Of Stress-activated MAPK Cascade Inner Ear Development Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Neural Tube Development Mitochondrial Outer Membrane Permeabilization Positive Regulation Of MAP Kinase Activity Endothelial Cell Morphogenesis Tube Development Heart Morphogenesis Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Ear Development
Tagcloud ?			butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Difference) ?			butyrate demethylation derivation efficiency enhances greatly insights ips karyotypes klf4 microarrays naturally nutritional permeable piggybac pluripotency pluripotent refractory remarkable reprogramming retroviral sickle somatic stimulation substitutes supplement transgene transposon vectors
Tagcloud (Intersection) ?