PLOD3

Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Membrane Extracellular Matrix Extracellular Exosome
	Molecular Function	Catalytic Activity Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen Transferase Activity Glycosyltransferase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Small Molecule Binding Metal Ion Binding Procollagen Galactosyltransferase Activity Dioxygenase Activity
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Intracellular Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Lung Morphogenesis Basement Membrane Assembly
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Ascorbic acid
Diseases
GWAS		Blood protein levels ( 30072576) Cerebral amyloid angiopathy in Alzheimer’s disease ( 34020725)
Interacting Genes		20 interacting genes: CCDC85B COIL COL17A1 CRIP3 DPPA2 EFHC2 EHMT2 FAM153A IP6K2 KCTD9 KHNYN L3MBTL3 LINC00839 NAB2 RAB3IP RALY RHOU RHOXF2 SORBS3 ZNF620
Entrez ID		8985
HPRD ID		04347
Ensembl ID		ENSG00000106397
Uniprot IDs		O60568
PDB IDs		6FXK 6FXM 6FXR 6FXT 6FXX 6FXY 6TE3 6TEC 6TES 6TEU 6TEX 6TEZ 6WFV 8ONE
Enriched GO Terms of Interacting Partners?
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