PER2 and TPT1

Number of citations of the paper that reports this interaction (PMID 25103245)
1

Data Source:
BioGRID (two hybrid)

		PER2	TPT1
Gene Name		period circadian clock 2	tumor protein, translationally-controlled 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Perinuclear Region Of Cytoplasm	Extracellular Space Nucleus Cytoplasm Multivesicular Body Tubulin Complex Extracellular Vesicular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity Core Promoter Binding Transcription Corepressor Binding Transcription Coactivator Activity Signal Transducer Activity Protein Binding Kinase Binding Nuclear Hormone Receptor Binding Pre-mRNA Binding Histone Deacetylase Binding Ubiquitin Binding RNA Polymerase Binding Histone Methyltransferase Binding	Calcium Ion Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Transcription, DNA-templated Fatty Acid Metabolic Process Signal Transduction Circadian Rhythm Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of DNA-templated Transcription, Termination Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Negative Regulation Of Transcription Regulatory Region DNA Binding	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CRY1 CRY2 CSNK1D CSNK1E PER1 PER3 TIMELESS TP53 TPT1	25 interactors: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1D FANCA IKBKG LIG4 MCL1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A
Entrez ID		8864	7178
HPRD ID		04575	15979
Ensembl ID		ENSG00000132326	ENSG00000133112
Uniprot IDs		O15055	P13693 Q8TBK7
PDB IDs			1YZ1 2HR9 3EBM
Enriched GO Terms of Interacting Partners?		Regulation Of Circadian Rhythm Circadian Rhythm Rhythmic Process Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Blue Light Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Blue Light Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Light Stimulus Cellular Response To Light Stimulus Cellular Response To DNA Damage Stimulus Regulation Of Signal Transduction Protein-chromophore Linkage Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Response To Radiation Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Circadian Rhythm Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process DNA Repair Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Response To Stimulus Mitotic Cell Cycle Process Cell Cycle Phase Transition Mitotic Cell Cycle Cellular Response To Stress Cellular Response To Stimulus Response To External Stimulus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process	Regulation Of Response To DNA Damage Stimulus Cell Communication By Electrical Coupling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Stimulus Cellular Response To DNA Damage Stimulus Response To Organic Cyclic Compound Response To Glycoside Apoptotic Process Regulation Of The Force Of Heart Contraction Response To Radiation Programmed Cell Death Positive Regulation Of Mitotic Cell Cycle Cell Death Death Response To Steroid Hormone Response To Abiotic Stimulus Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Stress Sodium Ion Export From Cell Response To Lipid Regulation Of Signaling Cardiac Muscle Contraction Response To Stimulus Regulation Of Heart Contraction Neuron Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Sodium Ion Export Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Potassium Ion Homeostasis Cellular Response To Steroid Hormone Stimulus Neuron Death Cell Cycle Heart Contraction Cellular Response To Organic Cyclic Compound Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitotic Cell Cycle Regulation Of Cellular Localization Cellular Response To Lipid Regulation Of Cardiac Muscle Contraction Regulation Of Neurogenesis Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Apoptotic Process Muscle Contraction Regulation Of Cellular Process Negative Regulation Of Mitotic Cell Cycle Cellular Localization
Tagcloud ?		aperiodic arnt brighton brosens chan circadian clock conceptus congruently cryptochrome decidual decidualizing disorganized grossly hescs kaput lacey lucas midluteal miscarriages moore muter oscillations predicated preponderance quenby silences synchronizes uncoupling	2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates
Tagcloud (Difference) ?		aperiodic arnt brighton brosens chan circadian clock conceptus congruently cryptochrome decidual decidualizing disorganized grossly hescs kaput lacey lucas midluteal miscarriages moore muter oscillations predicated preponderance quenby silences synchronizes uncoupling	2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates
Tagcloud (Intersection) ?