TPT1 and ATP1A2

Number of citations of the paper that reports this interaction (PMID 15383549)
17

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		TPT1	ATP1A2
Gene Name		tumor protein, translationally-controlled 1	ATPase, Na+/K+ transporting, alpha 2 polypeptide
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Multivesicular Body Tubulin Complex Extracellular Vesicular Exosome	Cytoplasm Endosome Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola T-tubule Vesicle Dendritic Spine Synapse
	Molecular Function	Calcium Ion Binding Protein Binding Poly(A) RNA Binding	Sodium:potassium-exchanging ATPase Activity ATP Binding Metal Ion Binding Chaperone Binding Steroid Hormone Binding
	Biological Process	Calcium Ion Transport Cellular Calcium Ion Homeostasis Response To Virus Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Neurotransmitter Uptake Regulation Of The Force Of Heart Contraction Regulation Of Respiratory Gaseous Exchange By Neurological System Process Potassium Ion Transport Sodium Ion Transport Cellular Sodium Ion Homeostasis Regulation Of Smooth Muscle Contraction Regulation Of Striated Muscle Contraction Metabolic Process Regulation Of Blood Pressure Adult Locomotory Behavior Visual Learning Potassium Ion Import Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion ATP Hydrolysis Coupled Proton Transport Regulation Of Vasoconstriction Cellular Potassium Ion Homeostasis Ion Transmembrane Transport Response To Nicotine Sodium Ion Export From Cell Locomotion Negative Regulation Of Heart Contraction Negative Regulation Of Striated Muscle Contraction Negative Regulation Of Cytosolic Calcium Ion Concentration Transmembrane Transport Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Cellular Response To Mechanical Stimulus Cellular Response To Steroid Hormone Stimulus Regulation Of Cardiac Muscle Cell Contraction Membrane Depolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Glycoside
Pathways			Ion transport by P-type ATPases Ion channel transport
Drugs
Diseases
GWAS			Response to antipsychotic treatment ( 23241943)
Protein-Protein Interactions		25 interactors: APP ATP1A1 ATP1A2 BCL2L1 CALM1 DBN1 EEF1A1 EEF1D FANCA IKBKG LIG4 MCL1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 RPLP1 SNX6 SPP1 STEAP3 TRIP13 TUBB2A	1 interactors: TPT1
Entrez ID		7178	477
HPRD ID		15979	01665
Ensembl ID		ENSG00000133112	ENSG00000018625
Uniprot IDs		P13693 Q8TBK7	B4DIQ8 P50993
PDB IDs		1YZ1 2HR9 3EBM
Enriched GO Terms of Interacting Partners?		Regulation Of Response To DNA Damage Stimulus Cell Communication By Electrical Coupling Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Stimulus Cellular Response To DNA Damage Stimulus Response To Organic Cyclic Compound Response To Glycoside Apoptotic Process Regulation Of The Force Of Heart Contraction Response To Radiation Programmed Cell Death Positive Regulation Of Mitotic Cell Cycle Cell Death Death Response To Steroid Hormone Response To Abiotic Stimulus Response To Stress Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Response To Stress Sodium Ion Export From Cell Response To Lipid Regulation Of Signaling Cardiac Muscle Contraction Response To Stimulus Regulation Of Heart Contraction Neuron Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Sodium Ion Export Positive Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Cellular Potassium Ion Homeostasis Cellular Response To Steroid Hormone Stimulus Neuron Death Cell Cycle Heart Contraction Cellular Response To Organic Cyclic Compound Intracellular Receptor Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Mitotic Cell Cycle Regulation Of Cellular Localization Cellular Response To Lipid Regulation Of Cardiac Muscle Contraction Regulation Of Neurogenesis Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Apoptotic Process Muscle Contraction Regulation Of Cellular Process Negative Regulation Of Mitotic Cell Cycle Cellular Localization	Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Tagcloud ?		2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates	beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc2a1 slc2a1was slc2a3 slc2a4 slc2a5 slc37a4 slc5a1 washings
Tagcloud (Difference) ?		2o2 activating adds antioxidant avenue challenge chemoresistance complexity contain continuously correlation differentially direct diverse element existed fact lung maintains minimize mutated network open p53 promote responsive reversion stability upregulates	beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc2a1 slc2a1was slc2a3 slc2a4 slc2a5 slc37a4 slc5a1 washings
Tagcloud (Intersection) ?