STK19 and SP3

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		STK19	SP3
Gene Name		serine/threonine kinase 19	Sp3 transcription factor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane PML Body Transcriptional Repressor Complex
	Molecular Function	Protein Serine/threonine Kinase Activity ATP Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Double-stranded DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Ossification Natural Killer Cell Differentiation Trophectodermal Cell Differentiation Liver Development Embryonic Placenta Development Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter B Cell Differentiation T Cell Differentiation Megakaryocyte Differentiation Monocyte Differentiation Lung Development Granulocyte Differentiation Enucleate Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Embryonic Camera-type Eye Morphogenesis Embryonic Skeletal System Development Embryonic Process Involved In Female Pregnancy Definitive Hemopoiesis
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725) Hematology traits ( 23263863) Prostate cancer ( 23535732)
Protein-Protein Interactions		8 interactors: BHLHE40 POLE POLR2G PRAME SF3B4 SLC29A1 SP3 TRIM23	19 interactors: E2F1 EP300 ESR1 GABPA GCH1 GRIN1 HDAC1 HDAC2 HLTF NKX3-1 PIAS1 RB1 RBBP4 SP1 STK19 SUMO1 TP53 UBE2I ZBTB7A
Entrez ID		8859	6670
HPRD ID		07281	03483
Ensembl ID		ENSG00000204344	ENSG00000172845
Uniprot IDs		P49842	B7ZLN9 Q02447 Q59FX5 Q86TP0
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Transcription-coupled Nucleotide-excision Repair Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Uridine Transport Regulation Of MRNA Processing Nucleotide-excision Repair Pyrimidine Nucleoside Transport Cellular Metabolic Process RNA Metabolic Process Base-excision Repair, Gap-filling Transcription From RNA Polymerase II Promoter Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Embryonic Process Involved In Female Pregnancy Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Translational Initiation Enucleate Erythrocyte Differentiation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Granulocyte Differentiation Sleep DNA Synthesis Involved In DNA Repair RNA Splicing Nucleotide-excision Repair, DNA Gap Filling Regulation Of MRNA 3'-end Processing Nucleoside Transmembrane Transport Monocyte Differentiation Nucleoside Transport Natural Killer Cell Differentiation Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of MRNA Catabolic Process Regulation Of RNA Metabolic Process Megakaryocyte Differentiation Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Gene Expression Definitive Hemopoiesis Nuclear DNA Replication Telomere Maintenance Via Recombination Negative Regulation Of Biosynthetic Process	Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Rhythmic Process RNA Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Chromatin Organization Regulation Of Signaling Response To Organic Substance Biosynthetic Process Cellular Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signal Transduction Chromatin Modification Regulation Of Cell Cycle Chromatin Remodeling Intracellular Steroid Hormone Receptor Signaling Pathway Cellular Response To Organic Substance Chromosome Organization Regulation Of Cell Proliferation Mitotic Cell Cycle Cellular Response To Hypoxia
Tagcloud ?		acral amine awareness braf causative ctla4 dabrafenib etc exceptionally grin2a holds imatinib immunosuppressive instances mandatory mek melanoma melanomas nevertheless nras ppp6c prex2 rac1 revolution substitutions threonine trrap ultraviolet vemurafenib
Tagcloud (Difference) ?		acral amine awareness braf causative ctla4 dabrafenib etc exceptionally grin2a holds imatinib immunosuppressive instances mandatory mek melanoma melanomas nevertheless nras ppp6c prex2 rac1 revolution substitutions threonine trrap ultraviolet vemurafenib
Tagcloud (Intersection) ?