NRP2 and SEMA3B

Number of citations of the paper that reports this interaction (PubMedID 10196546)
0

Data Source:
HPRD (in vivo)

		NRP2	SEMA3B
Description		neuropilin 2	semaphorin 3B
Image			No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Extracellular Region Plasma Membrane Membrane Axon Postsynaptic Membrane Glutamatergic Synapse	Extracellular Region Endoplasmic Reticulum Plasma Membrane Extracellular Matrix
	Molecular Function	Vascular Endothelial Growth Factor Receptor Activity Protein Binding Heparin Binding Semaphorin Receptor Activity Growth Factor Binding Cytokine Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity
	Biological Process	Angiogenesis Neuron Migration Positive Regulation Of Endothelial Cell Proliferation Outflow Tract Septum Morphogenesis Cell Adhesion Nervous System Development Axon Guidance Heart Development Positive Regulation Of Endothelial Cell Migration Facial Nerve Structural Organization Trigeminal Nerve Structural Organization Vestibulocochlear Nerve Structural Organization Nerve Development Branchiomotor Neuron Axon Guidance Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Cell Differentiation Trunk Neural Crest Cell Migration Ventral Trunk Neural Crest Cell Migration Vascular Endothelial Growth Factor Signaling Pathway Axon Extension Involved In Axon Guidance Negative Chemotaxis Sympathetic Ganglion Development Trigeminal Ganglion Development Semaphorin-plexin Signaling Pathway Sensory Neuron Axon Guidance Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Regulation Of Postsynapse Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Facioacoustic Ganglion Development Dorsal Root Ganglion Morphogenesis Cellular Response To Leukemia Inhibitory Factor	Neural Crest Cell Migration Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Migration Negative Chemotaxis Chemorepulsion Of Axon Semaphorin-plexin Signaling Pathway
Pathways		Neurophilin interactions with VEGF and VEGFR NrCAM interactions
Drugs		ATYR1923
Diseases
GWAS		Blood protein levels ( 30072576) Craniofacial microsomia ( 26853712) Daytime nap ( 33568662) Diisocyanate-induced asthma ( 25918132) Neuropathy x type 2 diabetes interaction ( 32541925)	Obese vs. thin ( 30677029) Sleep duration (short sleep) ( 30846698) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		11 interacting genes: FLT1 L1CAM NRP1 PGF PLXNA1 PLXNB1 SEMA3B SEMA3C SEMA3F SEMA4F VEGFA	23 interacting genes: BOLL CARD10 CREBBP CYSRT1 HSF2BP KPRP KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP5-9 MDFI NAA10 NBPF19 NOTCH2NLA NRP1 NRP2 PAK6 PICK1 RBPMS2 SEMA3A TRIP13
Entrez ID		8828	7869
HPRD ID		03643	03179
Ensembl ID		ENSG00000118257	ENSG00000012171
Uniprot IDs		O60462	A0A0C4DGV8 B4DEK9 Q13214 Q6PI51
PDB IDs		2QQJ 2QQK 2QQL 2QQO 4QDQ 4QDR 4QDS 5DN2 5DQ0 6GH8 6TDB 6TJT 7M22 7T4S 8IVW 8IVX
Enriched GO Terms of Interacting Partners?		Semaphorin-plexin Signaling Pathway Chemotaxis Locomotion Neuron Projection Guidance Neuropilin Binding Semaphorin Receptor Binding Cell Migration Regulation Of Cell Migration Regulation Of Cell Motility Cell Motility Regulation Of Locomotion Axon Guidance Neuron Projection Development Neural Crest Cell Migration Regulation Of Axonogenesis Mesenchymal Cell Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Vascular Endothelial Growth Factor Signaling Pathway Cell Projection Organization Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Regulation Of Axon Extension Chemorepellent Activity Cell Surface Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Sprouting Angiogenesis Plasma Membrane Bounded Cell Projection Organization Negative Chemotaxis Ameboidal-type Cell Migration Regulation Of Neurogenesis Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Neuron Projection Development Regulation Of Nervous System Development Regulation Of Axon Extension Involved In Axon Guidance Positive Regulation Of Axonogenesis Regulation Of Anatomical Structure Morphogenesis Retinal Ganglion Cell Axon Guidance VEGF-activated Neuropilin Signaling Pathway Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Developmental Growth Negative Regulation Of Axon Extension Ventral Trunk Neural Crest Cell Migration Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Positive Regulation Of Axon Extension Vascular Endothelial Growth Factor Receptor Binding Sympathetic Neuron Projection Guidance Neuropilin Signaling Pathway	Sympathetic Neuron Projection Guidance Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Sympathetic Neuron Projection Extension Intermediate Filament Branchiomotor Neuron Axon Guidance Facial Nerve Structural Organization Sympathetic Ganglion Development Axon Extension Involved In Axon Guidance Ganglion Development Vestibulocochlear Nerve Structural Organization Anatomical Structure Arrangement Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Neuron Projection Arborization Ventral Trunk Neural Crest Cell Migration Neuron Projection Extension Basal Dendrite Arborization Basal Dendrite Morphogenesis Motor Neuron Axon Guidance Trigeminal Ganglion Development Cranial Ganglion Development Trunk Neural Crest Cell Migration Developmental Cell Growth Semaphorin-plexin Signaling Pathway Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Developmental Growth Involved In Morphogenesis Axon Extension Vascular Endothelial Growth Factor Receptor Activity Female Meiosis I Hypothalamus Cell Migration Neural Crest Cell Migration Mesenchymal Cell Migration Axonogenesis Involved In Innervation N-terminal Protein Amino Acid Acetylation Dendrite Arborization Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Axon Extension Involved In Axon Guidance Sympathetic Nervous System Development Keratin Filament Identical Protein Binding Acetyltransferase Activity Tissue Development Vascular Endothelial Growth Factor Signaling Pathway Female Meiotic Nuclear Division Developmental Process Male Meiosis I Outflow Tract Septum Morphogenesis
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