NRP2 and SEMA3C

Number of citations of the paper that reports this interaction (PMID 9331348)
85

Data Source:
HPRD (in vivo)

		NRP2	SEMA3C
Gene Name		neuropilin 2	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Semaphorin Receptor Complex Extracellular Region Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Space Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Vascular Endothelial Growth Factor-activated Receptor Activity Heparin Binding Semaphorin Receptor Activity Growth Factor Binding Cytokine Binding Metal Ion Binding	Receptor Activity Semaphorin Receptor Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Cell Adhesion Axon Guidance Positive Regulation Of Endothelial Cell Migration Nerve Development Vascular Endothelial Growth Factor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Axon Extension Involved In Axon Guidance Sympathetic Ganglion Development Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance	Neural Crest Cell Migration Somitogenesis Blood Vessel Remodeling Outflow Tract Morphogenesis Cardiac Right Ventricle Morphogenesis Pulmonary Myocardium Development Immune Response Axon Guidance Post-embryonic Development Neural Tube Development Response To Drug Limb Bud Formation Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching
Pathways		Axon guidance Signaling by VEGF Neurophilin interactions with VEGF and VEGFR L1CAM interactions NrCAM interactions
Drugs
Diseases
GWAS			Bilirubin levels ( 19414484)
Protein-Protein Interactions		8 interactors: FLT1 NRP1 PGF SEMA3B SEMA3C SEMA3F SEMA4F VEGFA	2 interactors: NRP1 NRP2
Entrez ID		8828	10512
HPRD ID		03643	04034
Ensembl ID		ENSG00000118257	ENSG00000075223
Uniprot IDs		O60462 Q7LBX6 Q7Z3T9	B4E2I9 F5H1Z7 Q99985
PDB IDs		2QQJ 2QQK 2QQL 2QQO
Enriched GO Terms of Interacting Partners?		Chemotaxis Axon Guidance Sprouting Angiogenesis Axonogenesis Axon Development Regulation Of Axon Extension Morphogenesis Of A Branching Epithelium Cell Morphogenesis Involved In Neuron Differentiation Morphogenesis Of A Branching Structure Locomotion Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Regulation Of Axon Extension Involved In Axon Guidance Vascular Endothelial Growth Factor Receptor Signaling Pathway Vascular Endothelial Growth Factor Signaling Pathway Cell Morphogenesis Involved In Differentiation Movement Of Cell Or Subcellular Component Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Axon Extension Cell Part Morphogenesis Regulation Of Cell Size Positive Regulation Of Retinal Ganglion Cell Axon Guidance VEGF-activated Neuropilin Signaling Pathway Neuron Development Response To External Stimulus Regulation Of Axonogenesis Cellular Response To Vascular Endothelial Growth Factor Stimulus Pattern Specification Process Ameboidal-type Cell Migration Cell Differentiation Cell Morphogenesis Blood Vessel Development Morphogenesis Of An Epithelium Neuron Differentiation Vasculature Development Cell Projection Organization Branching Morphogenesis Of An Epithelial Tube Patterning Of Blood Vessels Neural Crest Cell Migration Regulation Of Retinal Ganglion Cell Axon Guidance Tissue Morphogenesis Positive Regulation Of Endothelial Cell Proliferation System Development Negative Regulation Of Axonogenesis Neural Crest Cell Development Tube Development Coronary Artery Morphogenesis Regulation Of Developmental Growth Trigeminal Nerve Structural Organization	Vestibulocochlear Nerve Structural Organization Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Ventral Trunk Neural Crest Cell Migration Hypothalamus Cell Migration Neural Crest Cell Migration Involved In Autonomic Nervous System Development Trigeminal Ganglion Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Hypothalamus Cell Differentiation Axon Extension Involved In Axon Guidance Vestibulocochlear Nerve Development Sympathetic Ganglion Development Facial Nerve Structural Organization Facial Nerve Morphogenesis Cerebral Cortex Tangential Migration Ganglion Development Vascular Endothelial Growth Factor Signaling Pathway Parasympathetic Nervous System Development Anatomical Structure Arrangement Sympathetic Nervous System Development Hypothalamus Development Cellular Response To Vascular Endothelial Growth Factor Stimulus Semaphorin-plexin Signaling Pathway Forebrain Neuron Development Substrate-dependent Cell Migration Axon Extension Autonomic Nervous System Development Neural Crest Cell Migration Cranial Nerve Development Positive Regulation Of Endothelial Cell Migration Positive Regulation Of Endothelial Cell Proliferation Forebrain Neuron Differentiation Neuron Projection Extension Neural Crest Cell Development Forebrain Generation Of Neurons Neural Crest Cell Differentiation Positive Regulation Of Epithelial Cell Migration Developmental Cell Growth Regulation Of Endothelial Cell Proliferation Embryonic Pattern Specification Cerebral Cortex Cell Migration Diencephalon Development Nerve Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Limbic System Development Telencephalon Cell Migration
Tagcloud ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3	allograft ansan c1r ccl2 cd97 chip comparatively corneal cxcl6 endothelial f3 folds g1p3 genocheck hla ifi30 keratocytes korea ltd microarray normalization oligo pig platinum porcine rejection stroma stromal xenotransplantation
Tagcloud (Difference) ?		10a 200c 30a 30c arhgap5 cd36 cdh2 cdk5r1 chips cyp27b1 figure gemcitabine gna13 gp5 hist1h2bf hlf igsf3 ikbkb il32 intriguing mirs oxidoreductase pak7 putatively rab23 rap2a slc11a1 sod3 tp53i3	allograft ansan c1r ccl2 cd97 chip comparatively corneal cxcl6 endothelial f3 folds g1p3 genocheck hla ifi30 keratocytes korea ltd microarray normalization oligo pig platinum porcine rejection stroma stromal xenotransplantation
Tagcloud (Intersection) ?