SUCLG2 and SUCLG1

Number of citations of the paper that reports this interaction (PMID 10873456)
13

Data Source:
HPRD (in vitro)

		SUCLG2	SUCLG1
Gene Name		succinate-CoA ligase, GDP-forming, beta subunit	succinate-CoA ligase, alpha subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex (GDP-forming)	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex (GDP-forming) Extracellular Vesicular Exosome
	Molecular Function	Succinate-CoA Ligase (GDP-forming) Activity ATP Binding GTP Binding GDP Binding Protein Heterodimerization Activity	ATP Citrate Synthase Activity Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity GTP Binding GDP Binding Poly(A) RNA Binding Protein Heterodimerization Activity Cofactor Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)	Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs		Succinic acid
Diseases
GWAS		Corneal astigmatism ( 22144915) Height ( 20881960) IgE levels ( 23146381)
Protein-Protein Interactions		2 interactors: GPR143 SUCLG1	2 interactors: CHMP1B SUCLG2
Entrez ID		8801	8802
HPRD ID		06799	18128
Ensembl ID		ENSG00000172340	ENSG00000163541
Uniprot IDs		E9PDQ8 Q96I99	P53597
PDB IDs
Enriched GO Terms of Interacting Partners?		Eye Pigment Biosynthetic Process Succinyl-CoA Metabolic Process Eye Pigmentation Succinate Metabolic Process Calcium-mediated Signaling Using Intracellular Calcium Source Melanosome Organization Pigment Granule Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Tricarboxylic Acid Cycle Regulation Of Calcium-mediated Signaling Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Cellular Pigmentation Pigment Biosynthetic Process Aerobic Respiration Acyl-CoA Metabolic Process Developmental Pigmentation Calcium-mediated Signaling Neuropeptide Signaling Pathway Dicarboxylic Acid Metabolic Process Pigmentation Phosphatidylinositol-mediated Signaling Second-messenger-mediated Signaling Cellular Respiration Visual Perception Sensory Perception Of Light Stimulus Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization	Succinyl-CoA Metabolic Process Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Succinate Metabolic Process Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Tricarboxylic Acid Cycle Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Citrate Metabolic Process Regulation Of Centrosome Cycle Tricarboxylic Acid Metabolic Process Aerobic Respiration Acyl-CoA Metabolic Process Mitotic Sister Chromatid Segregation Vacuolar Transport Sister Chromatid Segregation Dicarboxylic Acid Metabolic Process Cytokinesis Nucleus Organization Regulation Of Mitotic Nuclear Division Regulation Of Microtubule Cytoskeleton Organization Cellular Respiration Regulation Of Microtubule-based Process Chromosome Segregation Regulation Of Cell Division
Tagcloud ?			autosomal c10orf2 cofactor controversial dguok dysmotility efficacious encephalomyopathic encephalopathy hepatocerebral heterogeneous hypotonia infancy mngie mpv17 mtdna myopathic neurogastrointestinal neurological neuropathy phenotypically polg recessive rrm2b sucla2 tk2 tymp typically weakness
Tagcloud (Difference) ?			autosomal c10orf2 cofactor controversial dguok dysmotility efficacious encephalomyopathic encephalopathy hepatocerebral heterogeneous hypotonia infancy mngie mpv17 mtdna myopathic neurogastrointestinal neurological neuropathy phenotypically polg recessive rrm2b sucla2 tk2 tymp typically weakness
Tagcloud (Intersection) ?