SUCLG1

Gene Name		succinate-CoA ligase, alpha subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex (GDP-forming) Extracellular Vesicular Exosome
	Molecular Function	ATP Citrate Synthase Activity Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity GTP Binding GDP Binding Poly(A) RNA Binding Protein Heterodimerization Activity Cofactor Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: CHMP1B SUCLG2
Entrez ID		8802
HPRD ID		18128
Ensembl ID		ENSG00000163541
Uniprot IDs		P53597
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinyl-CoA Metabolic Process Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Succinate Metabolic Process Regulation Of Mitotic Spindle Organization Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Tricarboxylic Acid Cycle Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Citrate Metabolic Process Regulation Of Centrosome Cycle Tricarboxylic Acid Metabolic Process Aerobic Respiration Acyl-CoA Metabolic Process Mitotic Sister Chromatid Segregation Vacuolar Transport Sister Chromatid Segregation Dicarboxylic Acid Metabolic Process Cytokinesis Nucleus Organization Regulation Of Mitotic Nuclear Division Regulation Of Microtubule Cytoskeleton Organization Cellular Respiration Regulation Of Microtubule-based Process Chromosome Segregation Regulation Of Cell Division
Tagcloud ?		autosomal c10orf2 cofactor controversial dguok dysmotility efficacious encephalomyopathic encephalopathy hepatocerebral heterogeneous hypotonia infancy mngie mpv17 mtdna myopathic neurogastrointestinal neurological neuropathy phenotypically polg recessive rrm2b sucla2 tk2 tymp typically weakness