SERPINB7 and ZCCHC2

Data Source: HiPPIP (Novel)

		SERPINB7	ZCCHC2
Name		serpin family B member 7	zinc finger CCHC-type containing 2
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Cytoplasm
	Molecular Function	Serine-type Endopeptidase Inhibitor Activity Peptidase Inhibitor Activity	Nucleic Acid Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Platelet-derived Growth Factor Production	None
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 ) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 ) Asthma ( 30929738 31361310 31619474 32296059 34103634 ) Asthma (age of onset) ( 31036433 ) Asthma (childhood onset) ( 30929738 31036433 ) Asthma onset (childhood vs adult) ( 30929738 ) Food allergy ( 29051540 ) Hen's egg allergy ( 29051540 ) Systolic blood pressure ( 29208002 )	A body shape index ( 34021172 ) Asthma (age of onset) ( 31036433 ) Asthma (childhood onset) ( 31036433 ) Bipolar disorder ( 31043756 33263727 ) Breastfeeding duration ( 25475840 ) Chronotype ( 30696823 ) Cognitive function in longevity ( 33607172 ) Menopause (age at onset) ( 29773799 ) Morning person ( 30696823 ) Pulse pressure ( 30224653 ) Serum albumin levels ( 23022100 ) Waist circumference adjusted for body mass index ( 34021172 )
Novel Interactors		10 novel interactors: FBXO22 HRH4 OGDH PHLPP1 PIGN RELCH RNF152 SLC5A2 TAX1BP1 ZCCHC2	7 novel interactors: ERCC1 HMSD MDM4 PHLPP1 PIGN RELCH SERPINB7
Interacting Genes		None recorded	2 interacting genes: RNF10 SHANK3
Entrez ID		8710	54877
HPRD ID		04524	11696
Ensembl ID		ENSG00000166396	ENSG00000141664
Uniprot IDs		A8K3Q8 O75635	Q9BRD4 Q9C0B9
PDB IDs		Not available	Not available