COL26A1 and SERPINH1

Number of citations of the paper that reports this interaction (PMID 12145293)
4

Data Source:
HPRD (two hybrid)

		COL26A1	SERPINH1
Gene Name		collagen, type XXVI, alpha 1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Trimer Endoplasmic Reticulum Lumen Golgi Apparatus Plasma Membrane Extracellular Matrix	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Extracellular Vesicular Exosome
	Molecular Function		Serine-type Endopeptidase Inhibitor Activity Collagen Binding Poly(A) RNA Binding Unfolded Protein Binding
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation
Pathways		Collagen formation Collagen degradation Collagen biosynthesis and modifying enzymes Degradation of the extracellular matrix	Collagen formation Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS			Height ( 20881960 22021425)
Protein-Protein Interactions		3 interactors: EMID1 SERPINH1 TBP	17 interactors: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 HIST1H1B HMP19 KLF13 PPARG SLC2A4 SLC35F6 UBQLN4 UBTF
Entrez ID		136227	871
HPRD ID		16405	02968
Ensembl ID		ENSG00000160963	ENSG00000149257
Uniprot IDs		Q96A83	A8K259 P50454
PDB IDs
Enriched GO Terms of Interacting Partners?		Collagen Biosynthetic Process Chondrocyte Development Involved In Endochondral Bone Morphogenesis Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Chromatin Silencing At RDNA Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Chondrocyte Development Cartilage Development Involved In Endochondral Bone Morphogenesis Transcription From RNA Polymerase I Promoter Protein Maturation Chromatin Silencing Transcription From RNA Polymerase III Promoter Collagen Fibril Organization Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Termination Collagen Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Endochondral Bone Morphogenesis Multicellular Organismal Macromolecule Metabolic Process Chondrocyte Differentiation Multicellular Organismal Metabolic Process DNA-templated Transcription, Elongation Negative Regulation Of Cellular Metabolic Process Gene Silencing	Negative Regulation Of DNA Replication DNA-templated Transcription, Initiation Regulation Of Cell Proliferation Negative Regulation Of DNA Metabolic Process Negative Regulation Of Cell Proliferation Regulation Of DNA Replication Cell Maturation Regulation Of Cellular Component Organization Transcription Initiation From RNA Polymerase II Promoter Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cellular Metabolic Process Brown Fat Cell Differentiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Metformin Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Replication Fork Arrest Response To Diuretic Amylopectin Biosynthetic Process Single Organism Reproductive Process Regulation Of Cellular Process Chromatin Organization Regulation Of Cholesterol Transporter Activity Cellular Response To Vitamin E DNA-templated Transcription, Elongation Reproductive Process Apoptotic Signaling Pathway Regulation Of Cell Growth Brain Development Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Protein Stabilization Macromolecule Biosynthetic Process Head Development Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Multicellular Organism Reproduction Steroid Hormone Mediated Signaling Pathway Meiosis I Membrane Organization DNA-dependent DNA Replication Cellular Response To Oxygen Levels Transcription From RNA Polymerase II Promoter Female Gonad Development Regulation Of Gene Expression Signal Transduction By P53 Class Mediator Development Of Primary Female Sexual Characteristics Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation
Tagcloud ?			act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe
Tagcloud (Difference) ?			act biochemical bones caused chaperones consequences deficiency destabilization disorder dominant encode fkbp10 forms genes genetic growing include interact little maturation mislocalization moderately mutant mutation posttranslational predominantly produce reveal secondarily severe
Tagcloud (Intersection) ?