CHRD and TWSG1

Number of citations of the paper that reports this interaction (PubMedID 11260715)
0

Data Source:
HPRD (in vitro)

		CHRD	TWSG1
Description		chordin	twisted gastrulation BMP signaling modulator 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Cytokine Binding BMP Binding	Protein Binding Heparin Binding Transforming Growth Factor Beta Binding
	Biological Process	Skeletal System Development Positive Regulation Of Mesenchymal Cell Proliferation Pattern Specification Process Dorsal/ventral Pattern Formation Spinal Cord Dorsal/ventral Patterning Negative Regulation Of Cell Migration BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Floor Plate Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Cell Adhesion System Development	Ossification Mesoderm Formation Negative Regulation Of Cytokine Production Chondrocyte Differentiation Salivary Gland Morphogenesis Tissue Development Hemopoiesis BMP Signaling Pathway Regulation Of BMP Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of BMP Signaling Pathway Negative Regulation Of BMP Signaling Pathway Forebrain Development Camera-type Eye Development Negative Regulation Of Osteoblast Differentiation Positive Regulation Of SMAD Protein Signal Transduction Negative Regulation Of CD4-positive, Alpha-beta T Cell Activation Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Platelet count ( 20139978 32888494) Plateletcrit ( 27863252 32888494)	Dental caries ( 23064961)
Interacting Genes		60 interacting genes: ADAMTSL4 ATN1 BMP1 BMP2 CATSPER1 CD36 CHRDL2 CYSRT1 F2R FXR1 FXR2 GATA1 HOXA1 HRG INCA1 KRT34 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP19-2 KRTAP19-5 KRTAP22-1 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 LCE1C LCE1F LCE5A LIN7A MEOX2 NBPF19 NOTCH2NLA NR0B2 NR4A3 NUFIP2 OTX1 PLSCR1 POU4F2 RGS17 SLC15A2 SMAD3 SPRY1 SPRY2 SPRY3 TLL1 TRIM42 TSPAN4 TWSG1	10 interacting genes: BMP1 BMP4 CHRD FAM209A FNDC9 GJA8 GPRC5D LRRC4C SGTA TNS2
Entrez ID		8646	57045
HPRD ID		04592	05443
Ensembl ID		ENSG00000090539	ENSG00000128791
Uniprot IDs		E7ESX1 Q8N2W7 Q9H2X0	Q9GZX9
PDB IDs			8BWA 8BWD 8BWI 8BWL 8BWM 8BWN
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Tissue Development Negative Regulation Of Cellular Response To Growth Factor Stimulus Epidermis Development Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Identical Protein Binding Positive Regulation Of Blood Coagulation Keratinization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Osteoblast Proliferation Pericardium Development Positive Regulation Of Coagulation Positive Regulation Of Cartilage Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Bud Elongation Involved In Lung Branching Developmental Process Animal Organ Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of ERK1 And ERK2 Cascade Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Mesoderm Formation Regulation Of Ras Protein Signal Transduction Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Epithelial To Mesenchymal Transition Transcription Coactivator Binding Negative Regulation Of Cell Population Proliferation Positive Regulation Of Osteoblast Proliferation Branch Elongation Of An Epithelium Inner Ear Development Nuclear Glucocorticoid Receptor Binding Hair Cycle Ossification Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Inner Ear Morphogenesis Positive Regulation Of Cell-matrix Adhesion Formation Of Primary Germ Layer MAPK Cascade Epithelium Development Regulation Of Wound Healing Negative Regulation Of Small GTPase Mediated Signal Transduction	Dorsal/ventral Pattern Formation Positive Regulation Of Cartilage Development Skeletal System Development Regionalization Negative Regulation Of Metanephric Comma-shaped Body Morphogenesis Bud Dilation Involved In Lung Branching Apoptotic Process Involved In Endocardial Cushion Morphogenesis Negative Regulation Of Mesenchymal Cell Proliferation Involved In Ureter Development Intermediate Mesodermal Cell Differentiation Regulation Of Mesenchymal Cell Proliferation Negative Regulation Of Metanephric S-shaped Body Morphogenesis Positive Regulation Of Cardiac Muscle Fiber Development Negative Regulation Of Glomerulus Development Negative Regulation Of BMP Signaling Pathway Regulation Of Cartilage Development Positive Regulation Of Primary MiRNA Processing Tendon Cell Differentiation Negative Regulation Of Branching Involved In Ureteric Bud Morphogenesis Camera-type Eye Development BMP Signaling Pathway Positive Regulation Of Branching Involved In Lung Morphogenesis TRC Complex Pattern Specification Process Growth Factor Activity Cartilage Development Ossification Apoptotic Process Involved In Heart Morphogenesis Regulation Of Osteoblast Differentiation Positive Regulation Of MiRNA Processing Negative Regulation Of Glomerular Mesangial Cell Proliferation Nephric Duct Formation Bronchus Development Positive Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Deltoid Tuberosity Development Epithelial Cell Proliferation Involved In Lung Morphogenesis Cardiac Jelly Development Eye Development Negative Regulation Of Immature T Cell Proliferation Prostate Gland Morphogenesis Epithelial-mesenchymal Cell Signaling Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Branching Involved In Lung Morphogenesis Telencephalon Regionalization Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Branching Involved In Prostate Gland Morphogenesis Glomerular Capillary Formation Pericyte Cell Differentiation Specification Of Animal Organ Position Regulation Of BMP Signaling Pathway Trachea Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?