CDC14A and CDC25B

Number of citations of the paper that reports this interaction (PMID 20956543)
7

Data Source:
BioGRID (enzymatic study)

		CDC14A	CDC25B
Gene Name		cell division cycle 14A	cell division cycle 25B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Spindle	Spindle Pole Nucleoplasm Cytoplasm Centrosome Cytosol
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding
	Biological Process	Cell Cycle Cell Proliferation Peptidyl-tyrosine Dephosphorylation Cell Division	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Oocyte Maturation Protein Phosphorylation Mitotic Nuclear Division Female Meiosis I Positive Regulation Of Cell Proliferation Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Cell Cycle Cell Division
Pathways		Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Regulation of mitotic cell cycle Cell Cycle, Mitotic APC/C-mediated degradation of cell cycle proteins	Cyclin A/B1 associated events during G2/M transition G2/M Transition S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G2-G2/M phases Cyclin B2 mediated events Cell Cycle, Mitotic
Drugs			Double Oxidized Cysteine Cysteinesulfonic Acid Methyl Mercury Ion
Diseases
GWAS
Protein-Protein Interactions		8 interactors: BRAP CDC25B CDC6 CHRM1 FZR1 KIF20A POLR2A TP53	25 interactors: AR AURKA BRSK1 BRSK2 CDC14A CDK1 CDK2 CHEK1 CREBBP CSNK2A1 CSNK2B ESR1 FHL3 KAT2B MAPK14 MAPK9 MAPKAPK2 MELK PGR SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ
Entrez ID		8556	994
HPRD ID		04614	00307
Ensembl ID		ENSG00000079335	ENSG00000101224
Uniprot IDs		F5H7B3 Q59EF4 Q9UNH5	B3KS38 B4DIG0 B4DRC3 G8JLH2 P30305 Q6MZW8
PDB IDs			1CWR 1CWS 1CWT 1QB0 1YM9 1YMD 1YMK 1YML 1YS0 2A2K 2IFD 2IFV 2UZQ 3FQT 3FQU
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Mitotic Cell Cycle Regulation Of Cell Cycle Cell Division Cell Cycle Process Regulation Of Cell Cycle Process Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Cell Proliferation Cell Cycle Checkpoint Regulation Of Cell Division Positive Regulation Of Cytokinesis Negative Regulation Of DNA Replication Mitotic Nuclear Division Regulation Of Cytokinesis DNA Metabolic Process Regulation Of Mitotic Cell Cycle Nucleotide-excision Repair Negative Regulation Of DNA Metabolic Process Negative Regulation Of Macromitophagy Transcription, RNA-templated Oligodendrocyte Apoptotic Process Positive Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Positive Regulation Of Cell Division DNA Repair Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Helicase Activity Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway DNA Damage Checkpoint Cell Proliferation Traversing Start Control Point Of Mitotic Cell Cycle Organelle Organization Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Positive Regulation Of Cell Proliferation Cellular Response To DNA Damage Stimulus Mitochondrial DNA Repair Activation Of Anaphase-promoting Complex Activity Regulation Of Mitotic Cell Cycle Phase Transition Ras Protein Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Positive Regulation Of Protein Modification Process	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Intrinsic Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Programmed Cell Death Cell Cycle Process Cell Death Death Multicellular Organismal Development Developmental Process System Development Signaling Anatomical Structure Development Regulation Of Apoptotic Process Cell Communication Phosphorylation Cellular Response To Stimulus Regulation Of Mitochondrion Organization Regulation Of Establishment Of Protein Localization Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Signal Transduction Phosphate-containing Compound Metabolic Process Protein Phosphorylation Cell Cycle Checkpoint Regulation Of Protein Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Signal Transduction DNA Damage Checkpoint Regulation Of Intracellular Transport Regulation Of Signal Transduction Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transport Mitotic Cell Cycle Regulation Of Cellular Localization Histone Phosphorylation G2 DNA Damage Checkpoint Response To Stimulus
Tagcloud ?		adhesion agilent bioinformatics cdkn1c cdkn2a clustering col6a3 ctnna3 cycles david differentially distinctly dysregulated experiment focal folds go hoxb4 hyperplastic itgb6 oligonucletide pairs regulated repeating resources scar scars tgfbeta1 twice	anticancer box constituent contrary elucidated exhibits forkhead foxm1 g2 garnered glioma gliomas inactivation m1 medicinal natural nevertheless oncogenic p21cip1 p27kip1 plumbagin plumbago quinonoid root sifoxm1 survivin transactivation transfection zeylanica
Tagcloud (Difference) ?		adhesion agilent bioinformatics cdkn1c cdkn2a clustering col6a3 ctnna3 cycles david differentially distinctly dysregulated experiment focal folds go hoxb4 hyperplastic itgb6 oligonucletide pairs regulated repeating resources scar scars tgfbeta1 twice	anticancer box constituent contrary elucidated exhibits forkhead foxm1 g2 garnered glioma gliomas inactivation m1 medicinal natural nevertheless oncogenic p21cip1 p27kip1 plumbagin plumbago quinonoid root sifoxm1 survivin transactivation transfection zeylanica
Tagcloud (Intersection) ?