CDC25B and BRSK2

Number of citations of the paper that reports this interaction (PMID 15150265)
11

Data Source:
HPRD (in vitro)

		CDC25B	BRSK2
Gene Name		cell division cycle 25B	BR serine/threonine kinase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleoplasm Cytoplasm Centrosome Cytosol	Cytoplasm Endoplasmic Reticulum Centrosome Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Kinase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity ATP Binding Protein Kinase Binding Tau-protein Kinase Activity
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Oocyte Maturation Protein Phosphorylation Mitotic Nuclear Division Female Meiosis I Positive Regulation Of Cell Proliferation Positive Regulation Of Cytokinesis Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Kinase Activity Positive Regulation Of Mitotic Cell Cycle Cell Division	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Exocytosis Mitotic Nuclear Division Axonogenesis Peptidyl-serine Phosphorylation Establishment Of Cell Polarity Neuron Differentiation Actin Cytoskeleton Reorganization Cell Division Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways		Cyclin A/B1 associated events during G2/M transition G2/M Transition S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G2-G2/M phases Cyclin B2 mediated events Cell Cycle, Mitotic
Drugs		Double Oxidized Cysteine Cysteinesulfonic Acid Methyl Mercury Ion
Diseases
GWAS
Protein-Protein Interactions		25 interactors: AR AURKA BRSK1 BRSK2 CDC14A CDK1 CDK2 CHEK1 CREBBP CSNK2A1 CSNK2B ESR1 FHL3 KAT2B MAPK14 MAPK9 MAPKAPK2 MELK PGR SFN YWHAB YWHAE YWHAH YWHAQ YWHAZ	4 interactors: CDC25B CDC25C VCP WEE1
Entrez ID		994	9024
HPRD ID		00307	11611
Ensembl ID		ENSG00000101224	ENSG00000174672
Uniprot IDs		B3KS38 B4DIG0 B4DRC3 G8JLH2 P30305 Q6MZW8	B3KVE9 B4DLY3 E9PLM7 Q8IWQ3
PDB IDs		1CWR 1CWS 1CWT 1QB0 1YM9 1YMD 1YMK 1YML 1YS0 2A2K 2IFD 2IFV 2UZQ 3FQT 3FQU
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cell Cycle Intrinsic Apoptotic Signaling Pathway G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Apoptotic Process Positive Regulation Of Signal Transduction Positive Regulation Of Intracellular Transport Programmed Cell Death Cell Cycle Process Cell Death Death Multicellular Organismal Development Developmental Process System Development Signaling Anatomical Structure Development Regulation Of Apoptotic Process Cell Communication Phosphorylation Cellular Response To Stimulus Regulation Of Mitochondrion Organization Regulation Of Establishment Of Protein Localization Regulation Of Cell Death Positive Regulation Of Apoptotic Signaling Pathway Signal Transduction Phosphate-containing Compound Metabolic Process Protein Phosphorylation Cell Cycle Checkpoint Regulation Of Protein Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Intracellular Signal Transduction DNA Damage Checkpoint Regulation Of Intracellular Transport Regulation Of Signal Transduction Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transport Mitotic Cell Cycle Regulation Of Cellular Localization Histone Phosphorylation G2 DNA Damage Checkpoint Response To Stimulus	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Nuclear Division Cell Division Mitotic Cell Cycle Process Mitotic Cell Cycle Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Regulation Of Cell Cycle Peptidyl-tyrosine Dephosphorylation Cell Cycle Process Cellular Protein Modification Process Protein Dephosphorylation Regulation Of Cell Division Cell Cycle Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Deubiquitination Protein Hexamerization Cellular Protein Metabolic Process Aggresome Assembly Regulation Of Mitotic Cell Cycle Translesion Synthesis Regulation Of Cellular Protein Metabolic Process Dephosphorylation Female Meiosis I Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Protein Metabolic Process Postreplication Repair Regulation Of Catalytic Activity Oocyte Maturation Gamete Generation Regulation Of Protein Kinase Activity Female Meiotic Division Regulation Of Kinase Activity Sexual Reproduction Phosphate-containing Compound Metabolic Process ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cytokinesis Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Oocyte Development Oocyte Differentiation Positive Regulation Of Protein Modification Process Organelle Organization Peptidyl-amino Acid Modification Regulation Of Cytokinesis Reproduction Cellular Response To Heat
Tagcloud ?		anticancer box constituent contrary elucidated exhibits forkhead foxm1 g2 garnered glioma gliomas inactivation m1 medicinal natural nevertheless oncogenic p21cip1 p27kip1 plumbagin plumbago quinonoid root sifoxm1 survivin transactivation transfection zeylanica	aicar ampk ampkbeta blunted brsk1 c433s caax cys433 farnesylated farnesylation fertile imidazolecarboxamide knockin lkb1 lkb1c433s lkb1s431a mark4 mimetic myristoylation nuak nuak1 phenformin prenylated raises riboside s431a ser431 sik3 snf1
Tagcloud (Difference) ?		anticancer box constituent contrary elucidated exhibits forkhead foxm1 g2 garnered glioma gliomas inactivation m1 medicinal natural nevertheless oncogenic p21cip1 p27kip1 plumbagin plumbago quinonoid root sifoxm1 survivin transactivation transfection zeylanica	aicar ampk ampkbeta blunted brsk1 c433s caax cys433 farnesylated farnesylation fertile imidazolecarboxamide knockin lkb1 lkb1c433s lkb1s431a mark4 mimetic myristoylation nuak nuak1 phenformin prenylated raises riboside s431a ser431 sik3 snf1
Tagcloud (Intersection) ?