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BARX2 and SRF
Number of citations of the paper that reports this interaction (PubMedID
11278942
)
0
Data Source:
HPRD
(in vitro)
BARX2
SRF
Description
BARX homeobox 2
serum response factor
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Transcription Regulator Complex
Golgi Apparatus
Cytosol
Actin Cytoskeleton
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
Sequence-specific Double-stranded DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA Binding
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Serum Response Element Binding
Chromatin DNA Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Sequence-specific DNA Binding
Protein Dimerization Activity
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Primary MiRNA Binding
DNA-binding Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Cartilage Condensation
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Myotube Differentiation
Skeletal Muscle Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Branching Involved In Blood Vessel Morphogenesis
Response To Hypoxia
In Utero Embryonic Development
Mesoderm Formation
Neuron Migration
Trophectodermal Cell Differentiation
Heart Looping
Morphogenesis Of An Epithelial Sheet
Cell Migration Involved In Sprouting Angiogenesis
Leukocyte Differentiation
Regulation Of DNA-templated Transcription
Transcription By RNA Polymerase II
Actin Filament Organization
Cell-matrix Adhesion
Gastrulation
Heart Development
Long-term Memory
Negative Regulation Of Cell Population Proliferation
Associative Learning
Response To Toxic Substance
Response To Hormone
Epithelial Structure Maintenance
Hippocampus Development
Tangential Migration From The Subventricular Zone To The Olfactory Bulb
Actin Cytoskeleton Organization
Contractile Actin Filament Bundle Assembly
Regulation Of Cell Adhesion
Platelet Activation
Platelet Formation
Negative Regulation Of Cell Migration
Thyroid Gland Development
Forebrain Development
Neuron Projection Development
Response To Cytokine
Megakaryocyte Development
Dorsal Aorta Morphogenesis
Wound Healing
Stress Fiber Assembly
Skin Morphogenesis
Positive Thymic T Cell Selection
Sarcomere Organization
Positive Regulation Of Cell Differentiation
Positive Regulation Of Axon Extension
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Smooth Muscle Contraction
Positive Regulation Of Transcription By Glucose
Muscle Cell Cellular Homeostasis
Filopodium Assembly
Thymus Development
Developmental Growth
Neuron Development
Axon Extension
Erythrocyte Development
Positive Regulation Of DNA-binding Transcription Factor Activity
Regulation Of Smooth Muscle Cell Differentiation
Positive Regulation Of Filopodium Assembly
Cardiac Myofibril Assembly
Angiogenesis Involved In Wound Healing
Hematopoietic Stem Cell Differentiation
Positive Regulation Of Transcription Initiation By RNA Polymerase II
Long-term Synaptic Depression
Face Development
Heart Trabecula Formation
Cardiac Muscle Cell Myoblast Differentiation
Lung Morphogenesis
Bronchus Cartilage Development
Trachea Cartilage Development
Cardiac Vascular Smooth Muscle Cell Differentiation
Eyelid Development In Camera-type Eye
Lung Smooth Muscle Development
Establishment Of Skin Barrier
Bicellular Tight Junction Assembly
Cellular Response To Glucose Stimulus
Primitive Streak Formation
Epithelial Cell-cell Adhesion
Cellular Senescence
Cell-cell Adhesion
Negative Regulation Of Amyloid-beta Clearance
Negative Regulation Of MiRNA Transcription
Positive Regulation Of MiRNA Transcription
Pathways
RHO GTPases Activate Formins
NGF-stimulated transcription
NGF-stimulated transcription
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Cardiogenesis
Regulation of NPAS4 gene transcription
Drugs
Diseases
GWAS
Breast cancer (
22383897
)
HDL cholesterol levels in HIV infection (
33109212
)
Night sleep phenotypes (
27126917
)
Refractive error (
32231278
)
Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis (
26980576
)
Spontaneous preterm birth with premature rupture of membranes (
31194736
)
Type 2 diabetes (
22238593
)
Interacting Genes
3 interacting genes:
FHL2
FHL3
SRF
71 interacting genes:
ALDH3A1
ATF6
BARX2
CAMK2A
CASP3
CASP6
CASP7
CASP8
CASP9
CD63
CEBPB
CIRBP
CREB1
CREBBP
CRIP2
CSNK2A1
ELK1
ELK4
ETV4
FHL1
FHL2
FHL3
FHL5
FLI1
FOXG1
FOXK1
GATA4
GTF2F1
GTF2I
HDAC4
HMGA1
HOPX
KAT5
KDM6A
MAPKAPK2
MINPP1
MRTFA
MRTFB
MYOCD
MYOD1
MYOG
NCOA1
NCOA6
NCOR2
NFKB1
NFYA
NKX2-3
NKX2-5
NKX3-1
OGT
PML
PRKDC
PRRX1
PYCARD
RARA
REL
RELA
RPS6KA1
RXRA
RXRG
SHBG
SP1
SRC
SRFBP1
SSRP1
TCF3
TEAD1
TRIM63
TRIP4
UBE2I
ZIC3
Entrez ID
8538
6722
HPRD ID
16074
02788
Ensembl ID
ENSG00000043039
ENSG00000112658
Uniprot IDs
Q9UMQ3
B4DU24
P11831
PDB IDs
1HBX
1K6O
1SRS
Enriched GO Terms of Interacting Partners
?
Heart Trabecula Formation
Z Disc
Serum Response Element Binding
Atrial Cardiac Muscle Cell Development
Bronchus Cartilage Development
Lung Smooth Muscle Development
Trachea Cartilage Development
Cardiac Vascular Smooth Muscle Cell Differentiation
Focal Adhesion
Ventricular Cardiac Muscle Cell Development
Actin Filament-based Process
Actin Cytoskeleton Organization
Positive Regulation Of Transcription By Glucose
Vascular Associated Smooth Muscle Cell Differentiation
Regulation Of Transcription By Glucose
Negative Regulation Of Amyloid-beta Clearance
Carbon Catabolite Regulation Of Transcription
Dorsal Aorta Morphogenesis
Primitive Streak Formation
Cardiac Muscle Cell Myoblast Differentiation
Primary MiRNA Binding
Tangential Migration From The Subventricular Zone To The Olfactory Bulb
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Calcium-mediated Signaling
Transcription Factor Binding
Response To Hormone
Skin Morphogenesis
Positive Thymic T Cell Selection
Long-term Synaptic Depression
Face Development
Positive T Cell Selection
Eyelid Development In Camera-type Eye
Angiogenesis Involved In Wound Healing
Trophectodermal Cell Differentiation
Regulation Of Amyloid-beta Clearance
Platelet Formation
Contractile Actin Filament Bundle Assembly
Stress Fiber Assembly
Filopodium Assembly
Cardiac Myofibril Assembly
Smooth Muscle Tissue Development
Epithelial Cell-cell Adhesion
Thymic T Cell Selection
Morphogenesis Of An Epithelial Sheet
Megakaryocyte Development
Hematopoietic Stem Cell Differentiation
Cardioblast Differentiation
Aorta Morphogenesis
Muscle Cell Cellular Homeostasis
Cell Migration Involved In Sprouting Angiogenesis
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Chromatin
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Biosynthetic Process
Nucleus
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Gene Expression
Nucleoplasm
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Primary Metabolic Process
Positive Regulation Of Metabolic Process
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Regulator Complex
Transcription Cis-regulatory Region Binding
DNA Binding
Animal Organ Development
Sequence-specific Double-stranded DNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Cell Differentiation
Negative Regulation Of RNA Metabolic Process
Cellular Developmental Process
Developmental Process
Negative Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Negative Regulation Of DNA-templated Transcription
Transcription By RNA Polymerase II
Negative Regulation Of RNA Biosynthetic Process
RNA Polymerase II Transcription Regulator Complex
Response To Lipid
Muscle Cell Differentiation
DNA-templated Transcription
Negative Regulation Of Macromolecule Biosynthetic Process
Response To Cytokine
Chromatin Binding
Negative Regulation Of Macromolecule Metabolic Process
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Tagcloud (Intersection)
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