BARX2

Description		BARX homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Golgi Apparatus Cytosol Actin Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cartilage Condensation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Myotube Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 22383897) HDL cholesterol levels in HIV infection ( 33109212) Night sleep phenotypes ( 27126917) Refractive error ( 32231278) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Type 2 diabetes ( 22238593)
Interacting Genes		3 interacting genes: FHL2 FHL3 SRF
Entrez ID		8538
HPRD ID		16074
Ensembl ID		ENSG00000043039
Uniprot IDs		Q9UMQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Heart Trabecula Formation Z Disc Serum Response Element Binding Atrial Cardiac Muscle Cell Development Bronchus Cartilage Development Lung Smooth Muscle Development Trachea Cartilage Development Cardiac Vascular Smooth Muscle Cell Differentiation Focal Adhesion Ventricular Cardiac Muscle Cell Development Actin Filament-based Process Actin Cytoskeleton Organization Positive Regulation Of Transcription By Glucose Vascular Associated Smooth Muscle Cell Differentiation Regulation Of Transcription By Glucose Negative Regulation Of Amyloid-beta Clearance Carbon Catabolite Regulation Of Transcription Dorsal Aorta Morphogenesis Primitive Streak Formation Cardiac Muscle Cell Myoblast Differentiation Primary MiRNA Binding Tangential Migration From The Subventricular Zone To The Olfactory Bulb Negative Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Calcium-mediated Signaling Transcription Factor Binding Response To Hormone Skin Morphogenesis Positive Thymic T Cell Selection Long-term Synaptic Depression Face Development Positive T Cell Selection Eyelid Development In Camera-type Eye Angiogenesis Involved In Wound Healing Trophectodermal Cell Differentiation Regulation Of Amyloid-beta Clearance Platelet Formation Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Filopodium Assembly Cardiac Myofibril Assembly Smooth Muscle Tissue Development Epithelial Cell-cell Adhesion Thymic T Cell Selection Morphogenesis Of An Epithelial Sheet Megakaryocyte Development Hematopoietic Stem Cell Differentiation Cardioblast Differentiation Aorta Morphogenesis Muscle Cell Cellular Homeostasis Cell Migration Involved In Sprouting Angiogenesis
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