KRTAP3-3 and PVR

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP3-3	PVR
Description		keratin associated protein 3-3	PVR cell adhesion molecule
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Adherens Junction Focal Adhesion Cell Surface Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Virus Receptor Activity Protein Binding Signaling Receptor Activity Receptor Ligand Activity Cell Adhesion Molecule Binding Cell Adhesion Mediator Activity
	Biological Process		Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Signal Transduction Natural Killer Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Symbiont Entry Into Host Cell Susceptibility To T Cell Mediated Cytotoxicity
Pathways		Keratinization	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Nectin/Necl trans heterodimerization
Drugs			Sphingosine Myristic acid
Diseases
GWAS			Alzheimer's disease ( 24755620) Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Mean platelet volume ( 27863252 32888494) Multiple sclerosis ( 21833088) Multiple sclerosis and HDL levels (pleiotropy) ( 26920376) Platelet distribution width ( 32888494)
Interacting Genes		78 interacting genes: ALDH3B1 ANAPC11 ARID5A ATG9A BEX2 CELF5 CERCAM CIMAP1B CTSZ CYSRT1 DCANP1 DCDC2B DMRT3 DOCK2 ERMAP FADS6 FAM168A FARS2 FOXC2 FOXH1 FOXP3 GNE GPS2 GSTP1 GUCD1 HOXA1 HR HYPK KLHL38 KRT83 KRTAP10-1 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP4-11 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-3 KRTAP9-8 LASP1 LCE1F LCE2B LCE3A LCE3C LCE3D LCE3E LCE4A LONRF1 LRRN4 MGAT5B MRPL23 MXD3 NR1D2 NTAQ1 NUFIP2 OLIG3 OTX1 P2RY6 PATZ1 PHLDA1 PITX1 PITX2 PLSCR3 PLSCR4 PRKAB2 PVR SHISA6 SMARCC1 SSC4D TNFRSF12A VENTX VGLL3 YPEL3 ZNF503	68 interacting genes: ADIPOQ ANKRD46 AP1M2 AQP10 BRICD5 C3orf52 CD226 CD47 CD96 CLDN19 CTXN3 CYB561A3 CYSRT1 DYNLT1 DYNLT3 EBP EDDM3B GPRC5D HHATL HOXA1 INSIG2 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-1 KRTAP3-3 KRTAP6-3 KRTAP9-3 MFSD11 NBPF19 NECTIN1 NECTIN3 NINJ1 NINJ2 NOTCH2NLA OLFM4 PGA4 PLA2G3 PLP2 PLPP6 RUSF1 SCD SLC30A2 SLC35B4 SLC41A2 SMIM1 SNAP47 SYS1 TAS2R19 TIGIT TM6SF2 TMBIM6 TMEM147 TMEM229B TMEM54 TMEM65 TMEM79 TSPO VAMP5 VTN WNK1 ZDHHC15 ZDHHC22 ZFPL1 ZFTRAF1
Entrez ID		85293	5817
HPRD ID		13939	01434
Ensembl ID		ENSG00000212899	ENSG00000073008
Uniprot IDs		Q9BYR6	A0A0A0MSA9 A0A0C4DG49 A8K4I1 P15151
PDB IDs			1DGI 1NN8 3EPC 3EPD 3EPF 3J8F 3J9F 3UDW 3URO 4FQP 6ARQ 6ISC 6O3O
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Hair Cycle Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Chromatin	Keratin Filament Intermediate Filament Apical Junction Complex Membrane Cell Adhesion Mediator Activity Establishment Of Protein Localization To Membrane Identical Protein Binding Membrane Destabilizing Activity Regulation Of Natural Killer Cell Mediated Immunity Cell-cell Contact Zone Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cochlea Morphogenesis Regeneration Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Protein Binding Cell Adhesion Positive Regulation Of Mast Cell Activation Steroid Biosynthetic Process Cholesterol Biosynthetic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?