KRTAP3-3 and P2RY6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP3-3	P2RY6
Description		keratin associated protein 3-3	pyrimidinergic receptor P2Y6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Plasma Membrane Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	G Protein-coupled ADP Receptor Activity G Protein-coupled Receptor Activity Protein Binding G Protein-coupled Purinergic Nucleotide Receptor Activity G Protein-coupled UDP Receptor Activity G Protein-coupled UTP Receptor Activity
	Biological Process		Phagocytosis Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Transepithelial Chloride Transport Positive Regulation Of Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Prostaglandin E Stimulus Cellular Response To Purine-containing Compound Cellular Response To Oxygen-containing Compound Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Cellular Response To Pyrimidine Ribonucleotide
Pathways		Keratinization	G alpha (q) signalling events P2Y receptors
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		78 interacting genes: ALDH3B1 ANAPC11 ARID5A ATG9A BEX2 CELF5 CERCAM CIMAP1B CTSZ CYSRT1 DCANP1 DCDC2B DMRT3 DOCK2 ERMAP FADS6 FAM168A FARS2 FOXC2 FOXH1 FOXP3 GNE GPS2 GSTP1 GUCD1 HOXA1 HR HYPK KLHL38 KRT83 KRTAP10-1 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP4-11 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-3 KRTAP9-8 LASP1 LCE1F LCE2B LCE3A LCE3C LCE3D LCE3E LCE4A LONRF1 LRRN4 MGAT5B MRPL23 MXD3 NR1D2 NTAQ1 NUFIP2 OLIG3 OTX1 P2RY6 PATZ1 PHLDA1 PITX1 PITX2 PLSCR3 PLSCR4 PRKAB2 PVR SHISA6 SMARCC1 SSC4D TNFRSF12A VENTX VGLL3 YPEL3 ZNF503	16 interacting genes: CFTR HOXA1 KRTAP1-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP3-3 KRTAP5-9 KRTAP9-2 MCFD2 NBPF19 NOTCH2NLA PLSCR1
Entrez ID		85293	5031
HPRD ID		13939	03906
Ensembl ID		ENSG00000212899	ENSG00000171631
Uniprot IDs		Q9BYR6	Q15077
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Hair Cycle Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Chromatin	Intermediate Filament Keratin Filament
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