KRTAP3-3 and ARID5A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP3-3	ARID5A
Description		keratin associated protein 3-3	AT-rich interaction domain 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus
	Molecular Function	Structural Molecule Activity Protein Binding	Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding Transcription Corepressor Activity RNA Binding Protein Binding Transcription Factor Binding Nuclear Estrogen Receptor Binding RNA Stem-loop Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Sequence-specific DNA Binding Nuclear Retinoid X Receptor Binding Nuclear Thyroid Hormone Receptor Binding Nuclear Androgen Receptor Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Chondrocyte Differentiation Immune System Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Innate Immune Response Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide Cellular Response To Estrogen Stimulus Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of T-helper 1 Cell Cytokine Production
Pathways		Keratinization
Drugs
Diseases
GWAS			Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 27863252 32888494) Event-related brain oscillations ( 21184583)
Interacting Genes		78 interacting genes: ALDH3B1 ANAPC11 ARID5A ATG9A BEX2 CELF5 CERCAM CIMAP1B CTSZ CYSRT1 DCANP1 DCDC2B DMRT3 DOCK2 ERMAP FADS6 FAM168A FARS2 FOXC2 FOXH1 FOXP3 GNE GPS2 GSTP1 GUCD1 HOXA1 HR HYPK KLHL38 KRT83 KRTAP10-1 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP19-7 KRTAP4-11 KRTAP4-2 KRTAP5-6 KRTAP6-2 KRTAP9-3 KRTAP9-8 LASP1 LCE1F LCE2B LCE3A LCE3C LCE3D LCE3E LCE4A LONRF1 LRRN4 MGAT5B MRPL23 MXD3 NR1D2 NTAQ1 NUFIP2 OLIG3 OTX1 P2RY6 PATZ1 PHLDA1 PITX1 PITX2 PLSCR3 PLSCR4 PRKAB2 PVR SHISA6 SMARCC1 SSC4D TNFRSF12A VENTX VGLL3 YPEL3 ZNF503	127 interacting genes: ACTMAP ANKRD11 AR ATP6V0D2 ATXN1 ATXN1L BAG4 BAHD1 BANP BOLL C14orf119 CAMK2A CATSPER1 CCDC120 CCDC57 CKS1B COX5B CRYBA1 CRYBA2 CYSRT1 DAB1 DAZAP2 DOK6 DTX2 ESR2 ESRP1 FAM168B FHL3 FOXD2 FOXH1 GATA5 GLIS2 GOLGA2 GRB2 HDAC7 HOXA1 HSD3B7 INIP IRX6 KAZN KCTD9 KDF1 KRT40 KRTAP10-8 KRTAP12-2 KRTAP12-4 KRTAP15-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP22-1 KRTAP26-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LASP1 LENG8 LIMS3 LIMS4 LITAF LMO2 MAB21L2 MAGED1 MDFI MIEN1 MKRN3 MORN3 MYLIP NUDT22 ODAM OLIG3 OTX1 PHF1 PIBF1 PIN1 PITX1 PLA2G10 PLAGL2 PLEKHN1 PNMA1 POU1F1 PRDM6 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RARA RBFOX1 RBPMS RBPMS2 RFC5 RHOXF2 RNF44 ROR2 RXRA SEC24A SH2D2A SMYD1 SOHLH1 SOX5 TEKT3 TEKT4 TENT5A TENT5D TGM7 THRA TNS2 TRAF1 TRIM27 TRIM73 TSC1 TSEN15 TSSK3 UBTD2 USP20 VAC14 VENTX ZC3H10 ZIC1 ZNF503 ZNF765
Entrez ID		85293	10865
HPRD ID		13939	12481
Ensembl ID		ENSG00000212899	ENSG00000196843
Uniprot IDs		Q9BYR6	Q03989
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Tissue Development Hair Cycle Phospholipid Scramblase Activity Plasma Membrane Phospholipid Scrambling Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding Chromatin	Intermediate Filament Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Transcription Cis-regulatory Region Binding Identical Protein Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of DNA-templated Transcription Nuclear Receptor-mediated Signaling Pathway Sequence-specific Double-stranded DNA Binding Regulation Of RNA Biosynthetic Process DNA Binding Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Thyroid Hormone Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Spinal Cord Motor Neuron Migration POZ Domain Binding Regulation Of Gene Expression Chromatin Positive Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process Nuclear Steroid Receptor Activity Retinoic Acid Receptor Signaling Pathway Regulation Of Metabolic Process Regulation Of Thyroid Hormone Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Zinc Ion Binding Nucleus Retinoic Acid-responsive Element Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System
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