PVR and PVRL3

Number of citations of the paper that reports this interaction (PMID 12759359)
10

Data Source:
HPRD (in vitro)

		PVR	PVRL3
Gene Name		poliovirus receptor	poliovirus receptor-related 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Focal Adhesion Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome	Plasma Membrane Cell-cell Adherens Junction Integral Component Of Membrane Apical Junction Complex Postsynaptic Membrane
	Molecular Function	Virus Receptor Activity Receptor Activity Protein Binding Cell Adhesion Molecule Binding	Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Response To Virus Viral Process Single Organismal Cell-cell Adhesion Cell Migration Cell Junction Assembly Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Cell-cell Junction Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response Susceptibility To T Cell Mediated Cytotoxicity	Lens Morphogenesis In Camera-type Eye Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Fertilization Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Retina Morphogenesis In Camera-type Eye
Pathways		Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System	Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS		Multiple sclerosis ( 21833088)
Protein-Protein Interactions		18 interactors: AP1M2 CD226 CD96 DYNLT1 DYNLT3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 NOTCH2NL PLA2G3 PVRL1 PVRL3 SLC30A2 TIGIT TNFRSF12A VTN WNK1	13 interactors: KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 MLLT4 NOTCH2NL PARD3 PVR PVRL1 PVRL2 RGS20 TIGIT
Entrez ID		5817	25945
HPRD ID		01434	08454
Ensembl ID		ENSG00000073008
Uniprot IDs		P15151	Q9NQS3
PDB IDs		1DGI 1NN8 3EPC 3EPD 3EPF 3UDW 3URO 4FQP	4FOM
Enriched GO Terms of Interacting Partners?		Cell Adhesion Lens Morphogenesis In Camera-type Eye Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Immune System Process Positive Regulation Of Sequestering Of Zinc Ion Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Adherens Junction Organization Lens Development In Camera-type Eye Anatomical Structure Morphogenesis Cell Differentiation Interaction With Host Organelle Localization Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Substrate-dependent Cell Migration, Cell Attachment To Substrate Regulation Of Wound Healing Camera-type Eye Morphogenesis Negative Regulation Of Pancreatic Juice Secretion Intracellular Transport Of Viral Protein In Host Cell Transport Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Viral Process Eye Morphogenesis Retina Development In Camera-type Eye Enamel Mineralization Positive Regulation Of Immune Response To Tumor Cell Immune Response Viral Life Cycle Developmental Process Immune System Process Cell Junction Assembly Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Sperm Axoneme Assembly Tooth Mineralization Cell-cell Junction Organization Cell-substrate Adhesion Positive Regulation Of Systemic Arterial Blood Pressure Lipoxygenase Pathway Desmosome Organization Cell Adhesion Mediated By Integrin Positive Regulation Of Mast Cell Activation Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Phosphatidylglycerol Acyl-chain Remodeling Acrosome Assembly Amelogenesis Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway	Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Susceptibility To T Cell Mediated Cytotoxicity Viral Entry Into Host Cell Entry Into Host Cell Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune Response To Tumor Cell Interaction With Host Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Viral Life Cycle Response To Virus Cellular Component Assembly Coreceptor-mediated Virion Attachment To Host Cell Positive Regulation Of T Cell Mediated Cytotoxicity Cell Adhesion Regulation Of T Cell Mediated Cytotoxicity Locomotion Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Regulation Of Leukocyte Mediated Cytotoxicity Viral Process Sperm Mitochondrion Organization Fusion Of Virus Membrane With Host Plasma Membrane Positive Regulation Of Adaptive Immune Response Response To Other Organism Response To Biotic Stimulus Positive Regulation Of Innate Immune Response Regulation Of Adaptive Immune Response Cell Development Apical Constriction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Epithelial Cell Development Establishment Of Endothelial Intestinal Barrier Asymmetric Cell Division Cell Differentiation Cell Part Morphogenesis Enamel Mineralization Virion Attachment To Host Cell Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Regulation Of Innate Immune Response Adhesion Of Symbiont To Host Positive Regulation Of Myelination Tooth Mineralization
Tagcloud ?		advance catheterization collaborative consensus epoprostenol glaxo hemodynamic investigators mailed multicenter nc nineteen optimize output page pap park pph pulmonary responded routinely scheduled survey thirds triangle unresponsive vasodilator wellcome worsening
Tagcloud (Difference) ?		advance catheterization collaborative consensus epoprostenol glaxo hemodynamic investigators mailed multicenter nc nineteen optimize output page pap park pph pulmonary responded routinely scheduled survey thirds triangle unresponsive vasodilator wellcome worsening
Tagcloud (Intersection) ?