SRSF4 and GEMIN2

Number of citations of the paper that reports this interaction (PMID 9447963)
8

Data Source:
HPRD (two hybrid)

		SRSF4	GEMIN2
Gene Name		serine/arginine-rich splicing factor 4	gem (nuclear organelle) associated protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex Gemini Of Coiled Bodies
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Hematopoietic Progenitor Cell Differentiation Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Processing MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Negative Regulation Of MRNA Splicing, Via Spliceosome	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Gene Expression NcRNA Metabolic Process
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF1 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B ZDHHC17	21 interactors: DDX20 DHX9 GEMIN5 IKBKG RN7SL1 RNU1-1 RNU2-1 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		6429	8487
HPRD ID		09052	03999
Ensembl ID		ENSG00000116350	ENSG00000092208
Uniprot IDs		Q08170	O14893
PDB IDs			2LEH 3S6N
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Gene Expression Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nuclear Export Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus RNA Export From Nucleus Regulation Of Alternative MRNA Splicing, Via Spliceosome Ribonucleoprotein Complex Assembly Termination Of RNA Polymerase II Transcription MRNA Transport Cellular Metabolic Process Nucleocytoplasmic Transport Nuclear Transport RNA Transport RNA Localization Ribonucleoprotein Complex Biogenesis Negative Regulation Of MRNA Splicing, Via Spliceosome DNA-templated Transcription, Termination Negative Regulation Of RNA Splicing MRNA 3'-end Processing Regulation Of RNA Metabolic Process RNA 3'-end Processing Regulation Of Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly MRNA Splice Site Selection Ubiquitin-dependent SMAD Protein Catabolic Process Cellular Macromolecular Complex Assembly Regulation Of Gene Expression Cytoplasmic Transport Metabolic Process MRNA Cis Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Intracellular Transport Regulation Of Metabolic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Ribonucleoprotein Complex Assembly RNA Metabolic Process Gene Expression DNA-templated Transcription, Termination MRNA 3'-end Processing Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Cellular Nitrogen Compound Metabolic Process RNA Export From Nucleus Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Nuclear Export MRNA Transport NcRNA Metabolic Process RNA Transport RNA Localization Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing Nucleocytoplasmic Transport Nuclear Transport Cellular Component Assembly Neutrophil Degranulation Neutrophil Activation Involved In Immune Response Transcription From RNA Polymerase II Promoter Establishment Of Localization In Cell Cellular Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Neutrophil Mediated Immunity Neutrophil Activation Cytoplasmic Transport Cellular Localization Positive Regulation Of RNA Splicing Leukocyte Degranulation Regulation Of MRNA Stability Regulated Secretory Pathway
Tagcloud ?		abundant altering changed clk decay deep detained detention dis dramatic evolutionarily half hour intron introns lives mdm4 nmd nonsense polyadenylated pools shift splicing subject thousands transcript triggered undergoes widespread	associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Difference) ?		abundant altering changed clk decay deep detained detention dis dramatic evolutionarily half hour intron introns lives mdm4 nmd nonsense polyadenylated pools shift splicing subject thousands transcript triggered undergoes widespread	associates atrophy characterised efficiently epitope epitopes exists explain hela immunised immuno inherited library mab mabs mansma1 mansma12 mansma3 masked motor multimeric muscular phage precipitated precise proline smn spliceosome vigorous
Tagcloud (Intersection) ?