ZNF496 and JADE2

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZNF496	JADE2
Gene Name		zinc finger protein 496	jade family PHD finger 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Body	Histone Acetyltransferase Complex Nucleoplasm Extracellular Vesicular Exosome
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Protein Binding Protein Self-association Metal Ion Binding	Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Histone H3 Acetylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K12 Acetylation Histone H4-K16 Acetylation SMAD Protein Signal Transduction
Pathways		Generic Transcription Pathway	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ARR3 CBX3 JADE2 NR3C1 NSD1 POLR3D PPARG RAI1 SSX3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3	8 interactors: GORASP2 HIST3H3 ING4 ING5 PACSIN1 ZBTB3 ZBTB5 ZNF496
Entrez ID		84838	23338
HPRD ID		15805	15124
Ensembl ID		ENSG00000162714	ENSG00000043143
Uniprot IDs		Q96IT1	B3KPL2 D3DQA3 G3XAA4 Q9NQC1
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chromatin Modification Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process Chromosome Organization Positive Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Response To Metformin Response To Diuretic Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Glucocorticoid Mediated Signaling Pathway Peptidyl-lysine Modification Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA Demethylation Cellular Response To Vitamin E Regulation Of Cholesterol Transporter Activity Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Elongation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Glucocorticoid Mediated Signaling Pathway	Histone H3 Acetylation Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organelle Organization Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Growth Cellular Macromolecule Biosynthetic Process Peptidyl-lysine Modification Macromolecule Biosynthetic Process Histone H4-K12 Acetylation DNA Replication Chromosome Organization DNA Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transcription, DNA-templated DNA Damage Response, Signal Transduction Resulting In Transcription Histone H4-K5 Acetylation Histone H4-K8 Acetylation RNA Biosynthetic Process Membrane Tubulation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Modification Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Synaptic Vesicle Endocytosis Regulation Of Nitrogen Compound Metabolic Process Synaptic Vesicle Recycling
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