ZNF496 and POLR3D

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		ZNF496	POLR3D
Gene Name		zinc finger protein 496	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Body	Nuclear Chromatin Nucleoplasm DNA-directed RNA Polymerase III Complex Cytoplasm Cytosol
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Protein Binding Protein Self-association Metal Ion Binding	RNA Polymerase III Activity DNA Binding Chromatin Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated	Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Positive Regulation Of Interferon-beta Production Innate Immune Response Positive Regulation Of Innate Immune Response Defense Response To Virus
Pathways		Generic Transcription Pathway	RNA Polymerase III Transcription Termination RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Initiation From Type 2 Promoter Innate Immune System
Drugs
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		18 interactors: ARR3 CBX3 JADE2 NR3C1 NSD1 POLR3D PPARG RAI1 SSX3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZNF483 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3	13 interactors: APEX1 ATF3 HNRNPAB HOXA10 HOXC9 MAPK11 MSX2 NR2E3 POLR3E RBFOX2 RHOXF2 TAB1 ZNF496
Entrez ID		84838	661
HPRD ID		15805	01755
Ensembl ID		ENSG00000162714	ENSG00000168495
Uniprot IDs		Q96IT1	P05423
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Chromatin Modification Positive Regulation Of Macromolecule Biosynthetic Process Cellular Metabolic Process Chromosome Organization Positive Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Cellular Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Response To Metformin Response To Diuretic Low-density Lipoprotein Particle Receptor Biosynthetic Process Negative Regulation Of Pancreatic Stellate Cell Proliferation Glucocorticoid Mediated Signaling Pathway Peptidyl-lysine Modification Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA Demethylation Cellular Response To Vitamin E Regulation Of Cholesterol Transporter Activity Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Elongation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Glucocorticoid Mediated Signaling Pathway	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development Developmental Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Anatomical Structure Morphogenesis Positive Regulation Of Metabolic Process Intracellular Receptor Signaling Pathway Biosynthetic Process Anatomical Structure Development Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Anterior/posterior Pattern Specification Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway System Development Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?			address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Difference) ?			address ago1 antisense argonaute cis cytoplasm directed directs encoded existence h3k27me3 interference micrornas mir mirna mirnas orientation pcg polycomb posttranscriptional proximal rnai searched silence silencing start tgs transcriptionally tri
Tagcloud (Intersection) ?