ZNF496 and PGBD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		ZNF496	PGBD1
Description		zinc finger protein 496	piggyBac transposable element derived 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription	Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Chromium levels ( 26025379) Platelet distribution width ( 32888494)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hemoglobin levels ( 32327693) Kawasaki disease ( 33106546) Lung cancer ( 28604730) Myopia ( 27182965) Pulse pressure ( 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: ARR3 CBX3 JADE2 NR3C1 NSD1 PGBD1 POLR3D PPARG RAI1 RNF8 SCAND1 SSX3 SUMO2 SUMO3 SUPT5H TRIM28 ZKSCAN4 ZNF446 ZSCAN12 ZSCAN21 ZSCAN22 ZZZ3	8 interacting genes: MEOX2 NR4A1 TRAF2 ZKSCAN7 ZNF496 ZSCAN12 ZSCAN22 ZSCAN32
Entrez ID		84838	84547
HPRD ID		15805	11426
Ensembl ID		ENSG00000162714	ENSG00000137338
Uniprot IDs		Q96IT1	Q96JS3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Zinc Ion Binding Nucleus Chromatin Binding Nucleoplasm RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Protein Sumoylation Chromatin Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein Tag Activity DNA Binding Metal Ion Binding Nuclear Retinoid X Receptor Binding Positive Regulation Of RNA Metabolic Process SUMO Transferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Ubiquitin-like Protein Ligase Binding Negative Regulation Of DNA-templated Transcription, Elongation Cellular Response To Dexamethasone Stimulus RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Nuclear Glucocorticoid Receptor Activity Transcription Coregulator Binding Chromatin Remodeling Response To Dexamethasone Regulation Of DNA Binding Negative Regulation Of RNA Metabolic Process Protein Modification By Small Protein Conjugation Heterochromatin Positive Regulation Of Metabolic Process Cellular Response To Glucocorticoid Stimulus Positive Regulation Of MiRNA Transcription Nuclear Receptor Activity Chromatin Negative Regulation Of Connective Tissue Replacement Involved In Inflammatory Response Wound Healing	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Sequence-specific Double-stranded DNA Binding Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Metabolic Process TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex Detection Of Lipopolysaccharide Cellular Response To Corticotropin-releasing Hormone Stimulus Somite Specification CD27 Signaling Pathway Non-canonical Inflammasome Complex Assembly Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding
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