RTN4IP1 and RTN4R

Number of citations of the paper that reports this interaction (PMID 12160746)
84

Data Source:
HPRD (in vitro)

		RTN4IP1	RTN4R
Gene Name		reticulon 4 interacting protein 1	reticulon 4 receptor
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Gene Ontology Annotations	Cellular Component	Mitochondrion	Endoplasmic Reticulum Plasma Membrane Cell Surface Growth Cone Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Zinc Ion Binding Oxidoreductase Activity	Receptor Activity Protein Binding
	Biological Process	Oxidation-reduction Process	Axonogenesis Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis
Pathways			Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: CALCOCO2 EXOC7 RTN4 RTN4R WBP11 WIBG ZYX	6 interactors: LINGO1 MAG NGFR OMG RTN4 RTN4IP1
Entrez ID		84816	65078
HPRD ID		18008	16123
Ensembl ID			ENSG00000040608
Uniprot IDs		G3V1R2 Q8WWV3	Q9BZR6
PDB IDs		2VN8	1OZN 1P8T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Axonogenesis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Cellular Response To Growth Factor Stimulus Negative Regulation Of Neuron Projection Development Response To Growth Factor Negative Regulation Of Cell Projection Organization Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Axonogenesis Negative Regulation Of Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin Signaling Pathway Endoplasmic Reticulum Tubular Network Organization Negative Regulation Of Neurogenesis Response To Organic Substance Negative Regulation Of Cell Development Stress Fiber Assembly	Negative Regulation Of Axonogenesis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Regulation Of Axonogenesis Negative Regulation Of Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Neurogenesis Negative Regulation Of Cell Development Regulation Of Neuron Projection Development Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Neuron Differentiation Cellular Response To Growth Factor Stimulus Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Neurogenesis Negative Regulation Of Cell Differentiation Regulation Of Cell Development Enzyme Linked Receptor Protein Signaling Pathway Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Cellular Response To Organic Substance Neuron Projection Development Regulation Of Cellular Component Organization Neuron Development Central Nervous System Development Nervous System Development Neuron Differentiation Response To Organic Substance Cell Projection Organization Cell Surface Receptor Signaling Pathway Cell Differentiation Cell Development Regulation Of Cell Size Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Hair Follicle Development Regulation Of Branching Morphogenesis Of A Nerve System Development Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Hair Cycle Multicellular Organismal Development Endoplasmic Reticulum Tubular Network Organization Anatomical Structure Development Regulation Of Developmental Growth Signal Transduction Locomotion Positive Regulation Of Odontogenesis
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