RTN4IP1 and ERMN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RTN4IP1	ERMN
Description		reticulon 4 interacting protein 1	ermin
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Membrane	Cytoplasm Cytoskeleton Cell Cortex Filopodium Internode Region Of Axon Paranode Region Of Axon Neuronal Cell Body Myelin Sheath Extracellular Exosome Glial Cell Projection
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Ubiquinone Biosynthetic Process Nervous System Development Regulation Of Dendrite Development	Morphogenesis Of A Branching Structure Actin Filament Organization Regulation Of Cell Shape Regulation Of Cell Projection Organization
Pathways
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: ARFGAP3 CALCOCO2 CBFA2T3 CENPK CTAG1A CTAG1B ERMN EXOC7 GGA2 HDX MARCHF5 PPP1R8 PYM1 RELA RTN4 RTN4R RUNX1T1 SCAF1 SMURF2 SORBS1 WBP11 WWTR1 ZYX	3 interacting genes: APP NEDD4 RTN4IP1
Entrez ID		84816	57471
HPRD ID		18008	13838
Ensembl ID		ENSG00000130347	ENSG00000136541
Uniprot IDs		Q8WWV3	B4DIZ1 Q8TAM6
PDB IDs		2VN8
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process	Acetylcholine Receptor Activator Activity Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization PTB Domain Binding Regulation Of Spontaneous Synaptic Transmission Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway System Development Regulation Of Synapse Organization Response To Light Stimulus Intermediate-density Lipoprotein Particle Regulation Of Cell Projection Organization Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition NMDA Selective Glutamate Receptor Signaling Pathway Amylin Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Protein Catabolic Process Regulation Of Synapse Structure Or Activity Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Toll Signaling Pathway Regulation Of Monoatomic Ion Transmembrane Transport Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Monoatomic Cation Transmembrane Transport Synapse Organization Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Channel Inhibitor Activity Phosphoserine Residue Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Beta-2 Adrenergic Receptor Binding Phosphothreonine Residue Binding Regulation Of Dendrite Development Negative Regulation Of Potassium Ion Export Across Plasma Membrane
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