RTN4R

Gene Name		reticulon 4 receptor
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Cell Surface Growth Cone Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Protein Binding
	Biological Process	Axonogenesis Neurotrophin TRK Receptor Signaling Pathway Regulation Of Axonogenesis Negative Regulation Of Axonogenesis
Pathways		Signalling by NGF Axonal growth inhibition (RHOA activation) p75NTR regulates axonogenesis p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		6 interactors: LINGO1 MAG NGFR OMG RTN4 RTN4IP1
Entrez ID		65078
HPRD ID		16123
Ensembl ID		ENSG00000040608
Uniprot IDs		Q9BZR6
PDB IDs		1OZN 1P8T
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Axonogenesis Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Neuron Projection Development Negative Regulation Of Cell Projection Organization Regulation Of Axonogenesis Negative Regulation Of Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Neurogenesis Negative Regulation Of Cell Development Regulation Of Neuron Projection Development Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Neuron Differentiation Cellular Response To Growth Factor Stimulus Response To Growth Factor Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Neurogenesis Negative Regulation Of Cell Differentiation Regulation Of Cell Development Enzyme Linked Receptor Protein Signaling Pathway Generation Of Neurons Regulation Of Cell Differentiation Neurogenesis Cellular Response To Organic Substance Neuron Projection Development Regulation Of Cellular Component Organization Neuron Development Central Nervous System Development Nervous System Development Neuron Differentiation Response To Organic Substance Cell Projection Organization Cell Surface Receptor Signaling Pathway Cell Differentiation Cell Development Regulation Of Cell Size Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Negative Regulation Of Hair Follicle Development Regulation Of Branching Morphogenesis Of A Nerve System Development Positive Regulation Of Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Hair Cycle Multicellular Organismal Development Endoplasmic Reticulum Tubular Network Organization Anatomical Structure Development Regulation Of Developmental Growth Signal Transduction Locomotion Positive Regulation Of Odontogenesis
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