RTN4IP1 and PYM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RTN4IP1	PYM1
Description		reticulon 4 interacting protein 1	PYM1 exon junction complex associated factor
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Matrix Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cell Junction Exon-exon Junction Complex
	Molecular Function	Nucleotide Binding Protein Binding Zinc Ion Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity	RNA Binding Protein Binding Ribosome Binding
	Biological Process	Ubiquinone Biosynthetic Process Nervous System Development Regulation Of Dendrite Development	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Translation Positive Regulation Of Translation Exon-exon Junction Complex Disassembly
Pathways
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917) Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: ARFGAP3 CALCOCO2 CBFA2T3 CENPK CTAG1A CTAG1B ERMN EXOC7 GGA2 HDX MARCHF5 PPP1R8 PYM1 RELA RTN4 RTN4R RUNX1T1 SCAF1 SMURF2 SORBS1 WBP11 WWTR1 ZYX	6 interacting genes: APP NEDD4 NEDD4L POT1 PRNP RTN4IP1
Entrez ID		84816	84305
HPRD ID		18008	17940
Ensembl ID		ENSG00000130347	ENSG00000170473
Uniprot IDs		Q8WWV3	Q9BRP8
PDB IDs		2VN8
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process	Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Synapse Organization Regulation Of Monoatomic Ion Transmembrane Transport Sodium Channel Inhibitor Activity Regulation Of Potassium Ion Transport Plasma Membrane Bounded Cell Projection Organization Regulation Of Metal Ion Transport Potassium Channel Inhibitor Activity Regulation Of Dendrite Development Regulation Of Monoatomic Ion Transport Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Intracellular Copper Ion Homeostasis Transmembrane Transporter Binding Neuron Projection Development Cell Projection Organization Copper Ion Homeostasis Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Copper Ion Molecular Function Activator Activity Regulation Of Cellular Component Organization Positive Regulation Of Protein Catabolic Process Negative Regulation Of Potassium Ion Transport Response To Copper Ion Neuromuscular Junction Development Synapse Organization Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Receptor Metabolic Process Cellular Response To Amyloid-beta Regulation Of Amyloid Precursor Protein Catabolic Process Protein Monoubiquitination Positive Regulation Of Calcium-mediated Signaling Response To Metal Ion Response To Amyloid-beta Regulation Of Dendrite Morphogenesis Amyloid-beta Complex Growth Cone Lamellipodium System Development Regulation Of Response To Calcium Ion Positive Regulation Of Neuron Apoptotic Process Amylin Binding
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